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IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma.

Megan MontoyaSara A CollinsPavlina ChuntovaTrishna S PatelTakahide NejoAkane YamamichiNoriyuki KasaharaHideho Okada
Published in: bioRxiv : the preprint server for biology (2024)
expression of IRF8 may reduce immunosuppression and enhance antigen presentation, achieving improved tumor control.
Keyphrases
  • dendritic cells
  • poor prognosis
  • stem cells
  • case report
  • binding protein