Hideho Okada

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 45

Top Topics

Immune Response

Top Venues

bioRxiv : the preprint server for biology

Journal for immunotherapy of cancer

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Megan Montoya, Sara A Collins, Pavlina Chuntova, Trishna S Patel, Takahide Nejo, Akane Yamamichi, Noriyuki Kasahara, Hideho Okada
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. bioRxiv : the preprint server for biology (2024)
Rupesh R Kotecha, David Schiff, Arnab Chakravarti, Jessica L Fleming, Paul D Brown, Vinay K Puduvalli, Michael A Vogelbaum, Vinai Gondi, Marco Gallus, Hideho Okada, Minesh P Mehta
Multidisciplinary Management of Isocitrate Dehydrogenase-Mutated Gliomas in a Contemporary Molecularly Defined Era. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (21) (2024)
Megan Montoya, Sara A Collins, Pavlina Chuntova, Trishna S Patel, Takahide Nejo, Akane Yamamichi, Noriyuki Kasahara, Hideho Okada
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. bioRxiv : the preprint server for biology (2024)
Rupesh R Kotecha, David Schiff, Arnab Chakravarti, Jessica L Fleming, Paul D Brown, Vinay K Puduvalli, Michael A Vogelbaum, Vinai Gondi, Marco Gallus, Hideho Okada, Minesh P Mehta
Multidisciplinary Management of Isocitrate Dehydrogenase-Mutated Gliomas in a Contemporary Molecularly Defined Era. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (21) (2024)
Andrew J Hou, Ryan M Shih, Benjamin R Uy, Amanda Shafer, Ze Nan L Chang, Begonya Comin-Anduix, Miriam Guemes, Zoran Galic, Su Phyu, Hideho Okada, Katie B Grausam, Joshua J Breunig, Christine E Brown, David A Nathanson, Robert M Prins, Yvonne Y Chen
IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma. Neuro-oncology (2024)
Megan Montoya, Marco Gallus, Su Phyu, Jeffrey Haegelin, John de Groot, Hideho Okada
A Roadmap of CAR-T-Cell Therapy in Glioblastoma: Challenges and Future Perspectives. Cells 13 (9) (2024)
Megan Montoya, Marco Gallus, Su Phyu, Jeffrey Haegelin, John de Groot, Hideho Okada
A Roadmap of CAR-T-Cell Therapy in Glioblastoma: Challenges and Future Perspectives. Cells 13 (9) (2024)
Yutong Guo, Hohyun Lee, Chulyong Kim, Christian Park, Akane Yamamichi, Pavlina Chuntova, Marco Gallus, Miguel Oscar Bernabeu, Hideho Okada, Hanjoong Jo, Costas D Arvanitis
Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier. Nature communications 15 (1) (2024)
Rupesh R Kotecha, David Schiff, Arnab Chakravarti, Jessica L Fleming, Paul D Brown, Vinay K Puduvalli, Michael A Vogelbaum, Vinai Gondi, Marco Gallus, Hideho Okada, Minesh P Mehta
Multidisciplinary Management of Isocitrate Dehydrogenase-Mutated Gliomas in a Contemporary Molecularly Defined Era. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (21) (2024)
Megan Montoya, Sara A Collins, Pavlina Chuntova, Trishna S Patel, Takahide Nejo, Akane Yamamichi, Noriyuki Kasahara, Hideho Okada
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. Neuro-oncology (2024)
Megan Montoya, Sara A Collins, Pavlina Chuntova, Trishna S Patel, Takahide Nejo, Akane Yamamichi, Noriyuki Kasahara, Hideho Okada
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. Neuro-oncology (2024)
Darwin W Kwok, Hideho Okada, Joseph F Costello
Activating the dark genome to illuminate cancer vaccine targets. Nature genetics (2024)
Rupesh R Kotecha, David Schiff, Arnab Chakravarti, Jessica L Fleming, Paul D Brown, Vinay K Puduvalli, Michael A Vogelbaum, Vinai Gondi, Marco Gallus, Hideho Okada, Minesh P Mehta
Multidisciplinary Management of Isocitrate Dehydrogenase-Mutated Gliomas in a Contemporary Molecularly Defined Era. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Megan Montoya, Sara A Collins, Pavlina Chuntova, Trishna S Patel, Takahide Nejo, Akane Yamamichi, Noriyuki Kasahara, Hideho Okada
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. bioRxiv : the preprint server for biology (2024)
Megan Montoya, Sara A Collins, Pavlina Chuntova, Trishna S Patel, Takahide Nejo, Akane Yamamichi, Noriyuki Kasahara, Hideho Okada
IRF8-driven reprogramming of the immune microenvironment enhances anti-tumor adaptive immunity and reduces immunosuppression in murine glioblastoma. bioRxiv : the preprint server for biology (2024)
Megan Montoya, Marco Gallus, Su Phyu, Jeffrey Haegelin, John de Groot, Hideho Okada
A Roadmap of CAR-T-Cell Therapy in Glioblastoma: Challenges and Future Perspectives. Cells 13 (9) (2024)
Megan Montoya, Marco Gallus, Su Phyu, Jeffrey Haegelin, John de Groot, Hideho Okada
A Roadmap of CAR-T-Cell Therapy in Glioblastoma: Challenges and Future Perspectives. Cells 13 (9) (2024)
Rupesh R Kotecha, David Schiff, Arnab Chakravarti, Jessica L Fleming, Paul D Brown, Vinay K Puduvalli, Michael A Vogelbaum, Vinai Gondi, Marco Gallus, Hideho Okada, Minesh P Mehta
Multidisciplinary Management of Isocitrate Dehydrogenase-Mutated Gliomas in a Contemporary Molecularly Defined Era. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (21) (2024)
Lan Hoc Phung, Takahide Nejo, Hideho Okada
Lessons from Post-Immunotherapy Tumor Tissues in Clinical Trials: How Can We Fuel the Tumor Microenvironment in Gliomas? Vaccines 12 (8) (2024)
Andrew J Hou, Ryan M Shih, Benjamin R Uy, Amanda Shafer, Ze Nan L Chang, Begonya Comin-Anduix, Miriam Guemes, Zoran Galic, Su Phyu, Hideho Okada, Katie B Grausam, Joshua J Breunig, Christine E Brown, David A Nathanson, Robert M Prins, Yvonne Y Chen
IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma. Neuro-oncology (2024)
Takahide Nejo, Lin Wang, Kevin K Leung, Albert Wang, Senthilnath Lakshmanachetty, Marco Gallus, Darwin W Kwok, Chibo Hong, Lee H Chen, Diego A Carrera, Michael Y Zhang, Nicholas O Stevers, Gabriella C Maldonado, Akane Yamamichi, Payal Watchmaker, Akul Naik, Anny Shai, Joanna J Phillips, Susan M Chang, Arun P Wiita, James A Wells, Joseph F Costello, Aaron A Diaz, Hideho Okada
Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma. bioRxiv : the preprint server for biology (2023)
Marco Gallus, Darwin Kwok, Senthilnath Lakshmanachetty, Akane Yamamichi, Hideho Okada
Correction: Gallus et al. Immunotherapy Approaches in Isocitrate-Dehydrogenase-Mutant Low-Grade Glioma. Cancers 2023, 15 , 3726. Cancers 16 (1) (2023)
Juyeun Lee, Michael Nicosia, Ellen S Hong, Daniel J Silver, Cathy Li, Defne Bayik, Dionysios C Watson, Adam Lauko, Kristen E Kay, Sabrina Z Wang, Sarah Johnson, Mary McGraw, Matthew M Grabowski, Danielle D Kish, Amar B Desai, Wendy A Goodman, Scott J Cameron, Hideho Okada, Anna Valujskikh, Robert L Fairchild, Manmeet S Ahluwalia, Justin D Lathia
Sex-biased T cell exhaustion drives differential immune responses in glioblastoma. Cancer discovery (2023)
Zinal S Chheda, Sabine Mueller, Bindu Hegde, Akane Yamamichi, Lisa H Butterfield, Hideho Okada
Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Immisch et al . Journal for immunotherapy of cancer 11 (3) (2023)
Marco Gallus, Wolfgang Roll, Andre Dik, Cristina Barca, Bastian Zinnhardt, Gordon Hicking, Christoph Mueller, Venu Narayanan Naik, Max Anstötz, Julia Krämer, Leoni Rolfes, Lydia Wachsmuth, Julika Pitsch, Karen M J van Loo, Saskia J Raeuber, Hideho Okada, Catriona Wimberley, Christine Strippel, Kristin S Golombeck, Andreas Johnen, Stjepana Kovac, Catharina C Gross, Philipp Backhaus, Robert Seifert, Jan Lewerenz, Rainer Surges, Christian E Elger, Heinz Wiendl, Tobias Ruck, Albert J Becker, Cornelius Faber, Andreas H Jacobs, Jan Bauer, Sven Guenther Meuth, Michael Schäfers, Nico Melzer
Translational imaging of TSPO reveals pronounced innate inflammation in human and murine CD8 T cell-mediated limbic encephalitis. Science advances 9 (23) (2023)
David Gibson, Akshay Ravi, Eduardo Rodriguez, Susan Chang, Nancy Oberheim Bush, Jennie W Taylor, Jennifer L Clarke, David Solomon, Aaron Scheffler, John Witte, Hannah Lambing, Hideho Okada, Mitchel Berger, Farid Chehab, Nicholas A Butowski
Quantitative analysis of MGMT promoter methylation in glioblastoma suggests nonlinear prognostic effect. Neuro-oncology advances 5 (1) (2023)
Marco Gallus, Darwin Kwok, Senthilnath Lakshmanachetty, Akane Yamamichi, Hideho Okada
Immunotherapy Approaches in Isocitrate-Dehydrogenase-Mutant Low-Grade Glioma. Cancers 15 (14) (2023)
Takahide Nejo, Saritha Krishna, Christian Jimenez, Akane Yamamichi, Jacob S Young, Senthilnath Lakshmanachetty, Tiffany Chen, Su Su Sabai Phyu, Hirokazu Ogino, Payal Watchmaker, David Diebold, Abrar Choudhury, Andy G S Daniel, David R Raleigh, Shawn L Hervey-Jumper, Hideho Okada
Glioma-neuronal circuit remodeling induces regional immunosuppression. bioRxiv : the preprint server for biology (2023)
Marco Gallus, Darwin Kwok, Senthilnath Lakshmanachetty, Akane Yamamichi, Hideho Okada
Correction: Gallus et al. Immunotherapy Approaches in Isocitrate-Dehydrogenase-Mutant Low-Grade Glioma. Cancers 2023, 15 , 3726. Cancers 16 (1) (2023)
Ryusuke Hatae, Keith Kyewalabye, Akane Yamamichi, Tiffany Chen, Su Phyu, Pavlina Chuntova, Takahide Nejo, Lauren S Levine, Matthew H Spitzer, Hideho Okada
Enhancing CAR-T Cell Metabolism to Overcome Hypoxic Conditions in the Brain Tumor Microenvironment. bioRxiv : the preprint server for biology (2023)
Zinal S Chheda, Sabine Mueller, Bindu Hegde, Akane Yamamichi, Lisa H Butterfield, Hideho Okada
Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Immisch et al . Journal for immunotherapy of cancer 11 (3) (2023)
Marco Gallus, Darwin Kwok, Senthilnath Lakshmanachetty, Akane Yamamichi, Hideho Okada
Correction: Gallus et al. Immunotherapy Approaches in Isocitrate-Dehydrogenase-Mutant Low-Grade Glioma. Cancers 2023, 15 , 3726. Cancers 16 (1) (2023)
Darwin W Kwok, Nicholas O Stevers, Takahide Nejo, Lee H Chen, Inaki Etxeberria, Jangham Jung, Kaori Okada, Maggie Colton Cove, Senthilnath Lakshmanachetty, Marco Gallus, Abhilash Barpanda, Chibo Hong, Gary K L Chan, Samuel H Wu, Emilio Ramos, Akane Yamamichi, Jerry Liu, Payal Watchmaker, Hirokazu Ogino, Atsuro Saijo, Aidan Du, Nadia Grishanina, James Woo, Aaron Diaz, Susan M Chang, Joanna J Phillips, Arun P Wiita, Christopher A Klebanoff, Joseph F Costello, Hideho Okada
Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens. bioRxiv : the preprint server for biology (2023)
Atsuro Saijo, Hirokazu Ogino, Nicholas A Butowski, Meghan R Tedesco, David Gibson, Payal B Watchmaker, Kaori Okada, Albert S Wang, Anny Shai, Andres M Salazar, Annette M Molinaro, Jane E Rabbitt, Maryam Shahin, Arie Perry, Jennifer L Clarke, Jennie W Taylor, Mariza Daras, Nancy Ann Oberheim Bush, Shawn L Hervey-Jumper, Joanna J Phillips, Susan M Chang, Norbert Hilf, Andrea Mayer-Mokler, Tibor Keler, Mitchel S Berger, Hideho Okada
A combinatory vaccine with IMA950 plus varlilumab promotes effector memory T-cell differentiation in the peripheral blood of patients with low-grade gliomas. Neuro-oncology (2023)
Pavlina Chuntova, Akane Yamamichi, Tiffany Chen, Rohini Narayanaswamy, Sebastien Ronseaux, Christine Hudson, Adriana E Tron, Marc L Hyer, Megan Montoya, Abigail L Mende, Takahide Nejo, Kira M Downey, David Diebold, Min Lu, Brandon Nicolay, Hideho Okada
Inhibition of D-2HG leads to upregulation of a proinflammatory gene signature in a novel HLA-A2/HLA-DR1 transgenic mouse model of IDH1R132H-expressing glioma. Journal for immunotherapy of cancer 10 (5) (2022)
Julia Carnevale, Eric Shifrut, Nupura Kale, William A Nyberg, Franziska Blaeschke, Yan Yi Chen, Zhongmei Li, Sagar P Bapat, Morgan E Diolati, Patrick C O'Leary, Shane Vedova, Julia A Belk, Bence Daniel, Theodore L Roth, Stefanie Bachl, Alejandro Allo Anido, Brooke Prinzing, Jorge Ibañez-Vega, Shannon Lange, Dalia Haydar, Marie Luetke-Eversloh, Maelys Born-Bony, Bindu Hegde, Scott C Kogan, Tobias Feuchtinger, Hideho Okada, Ansuman T Satpathy, Kevin Shannon, Stephen Gottschalk, Justin Eyquem, Giedre Krenciute, Alan Ashworth, Alexander Marson
RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature 609 (7925) (2022)
Takayuki Ohkuri, Akemi Kosaka, Maki Ikeura, Andres M Salazar, Hideho Okada
IFN-γ- and IL-17-producing CD8+ T (Tc17-1) cells in combination with poly-ICLC and peptide vaccine exhibit antiglioma activity. Journal for immunotherapy of cancer 9 (6) (2022)
Pavlina Chuntova, Yafei Hou, Ryosuke Naka, Akane Yamamichi, Tiffany Chen, Yitzhar Goretsky, Ryusuke Hatae, Takahide Nejo, Gary Kohanbash, Abigail L Mende, Megan Montoya, Kira M Downey, David Diebold, Jayne Skinner, Hong-Erh Liang, Bjoern Schwer, Hideho Okada
Novel EGFRvIII-CAR transgenic mice for rigorous preclinical studies in syngeneic mice. Neuro-oncology (2021)
Paolo Antonio Ascierto, Carlo Bifulco, Jerome Galon, Claus Garbe, Samir N Khleif, Jennifer McQuade, Kunle Odunsi, Hideho Okada, Chrystal M Paulos, Sergio A Quezada, Hussein A Tawbi, John Timmerman, Giorgio Trinchieri, Lisa H Butterfield, Igor Puzanov
The Great Debate at 'Immunotherapy Bridge', Naples, December 5, 2019. Journal for immunotherapy of cancer 8 (2) (2021)
Erin F Simonds, Edbert D Lu, Oscar Badillo, Shokoufeh Karimi, Eric V Liu, Whitney Tamaki, Chiara Rancan, Kira M Downey, Jacob Stultz, Meenal Sinha, Lauren K McHenry, Nicole M Nasholm, Pavlina Chuntova, Anders Sundström, Vassilis Genoud, Shilpa A Shahani, Leo D Wang, Christine E Brown, Paul R Walker, Fredrik J Swartling, Lawrence Fong, Hideho Okada, William A Weiss, Mats Hellström
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. Journal for immunotherapy of cancer 9 (6) (2021)
Abigail L Mende, Jessica D Schulte, Hideho Okada, Jennifer L Clarke
Current Advances in Immunotherapy for Glioblastoma. Current oncology reports 23 (2) (2021)
Darwin Kwok, Hideho Okada
T-Cell based therapies for overcoming neuroanatomical and immunosuppressive challenges within the glioma microenvironment. Journal of neuro-oncology 147 (2) (2020)
Paula Alcaide-Leon, Tracy L Luks, Marisa Lafontaine, Janine M Lupo, Hideho Okada, Jennifer L Clarke, Javier E Villanueva-Meyer
Treatment-induced lesions in newly diagnosed glioblastoma patients undergoing chemoradiotherapy and heat-shock protein vaccine therapy. Journal of neuro-oncology 146 (1) (2019)
Bracha Shraibman, Eilon Barnea, Dganit Melamed Kadosh, Yael Haimovich, Gleb Slobodin, Itzhak Rosner, Carlos López-Larrea, Norbert Hilf, Sabrina Kuttruff, Colette Song, Cedrik Britten, John Castle, Sebastian Kreiter, Katrin Frenzel, Marcos Tatagiba, Ghazaleh Tabatabai, Pierre-Yves Dietrich, Valérie Dutoit, Wolfgang Wick, Michael Platten, Frank Winkler, Andreas von Deimling, Judith R Kroep, Juan Sahuquillo, Francisco Martínez-Ricarte, Jordi Rodon, Ulrik N Lassen, Christian Ottensmeier, Sjoerd H van der Burg, Per Thor Straten, Hans Skovgaard Poulsen, Berta Ponsati, Hideho Okada, Hans-Georg Rammensee, Ugur Sahin, Harpreet Singh, Arie Admon
Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma. Molecular & cellular proteomics : MCP 17 (11) (2018)
Zinal S Chheda, Gary Kohanbash, Kaori Okada, Naznin Jahan, John Sidney, Matteo Pecoraro, Xinbo Yang, Diego A Carrera, Kira M Downey, Shruti Shrivastav, Shuming Liu, Yi Lin, Chetana Lagisetti, Pavlina Chuntova, Payal B Watchmaker, Sabine Mueller, Ian F Pollack, Raja Rajalingam, Angel Montero Carcaboso, Matthias Mann, Alessandro Sette, K Christopher Garcia, Yafei Hou, Hideho Okada
Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy. The Journal of experimental medicine 215 (1) (2017)