The expression of the acarbose biosynthesis gene cluster in Actinoplanes sp. SE50/110 is dependent on the growth phase.

Julian DrosteVera OrtseifenLena SchaffertMarcus PersickeSusanne Schneiker-BekelAlfred PühlerJörn Kalinowski

Published in: BMC genomics (2020)

In conclusion, we have demonstrated, that a genome wide transcriptome and proteome analysis in a high temporal resolution is well suited to study the acarbose biosynthesis and the transcriptional and post-transcriptional regulation thereof.

Keyphrases

genome wide
dna methylation
copy number
gene expression
poor prognosis
cell wall
transcription factor
binding protein
single molecule
rna seq
heat shock
long non coding rna
heat stress
data analysis
heat shock protein