Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression.

Sidra MajazZhangwei TongKesong PengWei WangWenjing RenMing LiKun LiuPingli MoWengang LiChundong Yu

Published in: Cell & bioscience (2016)

Since AIB1 plays a promoting role in HCC progression, our results propose that GCN5 promotes HCC progression at least partially by regulating AIB1 expression. This study implicates that GCN5 might be a potential molecular target for HCC diagnosis and treatment.

Keyphrases

poor prognosis
dna methylation
binding protein
gene expression
long non coding rna
risk assessment
induced pluripotent stem cells
pluripotent stem cells