Longitudinal changes of SARA scale in Friedreich ataxia: Strong influence of baseline score and age at onset.

Luca PorcuMario FicheraLorenzo NanettiEliana RulliPaola GiuntiMichael H ParkinsonAlexandra DurrClaire EwenczykSylvia BoeschWolfgang NachbauerElisabetta IndelicatoThomas KlopstockClaudia StendelFrancisco Javier Rodríguez de RiveraLudger SchölsZofia FleszarIlaria GiordanoClaire DidszunAnna CastaldoMyriam RaiThomas KlockgetherMassimo PandolfoJörg Bernhard Schulz Kathrin Reetz Caterina Mariottinull null

Published in: Annals of clinical and translational neurology (2023)

Analyses of statistical properties of SARA suggest a variable sensitivity of the scale at different disease stages, and provide important information for population selection and result interpretation in future clinical trials.

Keyphrases

clinical trial
current status
early onset
cross sectional
health information
randomized controlled trial
phase ii
open label