High-performance liquid chromatography/electrospray ionisation mass spectrometric characterisation of metabolites produced by Pseudovibrio sp. W64, a marine sponge derived bacterium isolated from Irish waters.
Alka ChoudharyLynn M NaughtonAlan D W DobsonDilip K RaiPublished in: Rapid communications in mass spectrometry : RCM (2018)
Pseudovibrio sp. W64 produces methylated TDA in addition to TDA, and metabolises lipids and amino acids in the cell-culture medium. To the best of our knowledge, this is the first report of methylated TDA, cholic acid and its various analogs, and sphinganine being detected in this Pseudovibrio strain. The data generated may help to better understand the biochemical processes and metabolism of bacterial strains towards discovery of antimicrobial agents from marine sources.
Keyphrases
- high performance liquid chromatography
- mass spectrometry
- tandem mass spectrometry
- liquid chromatography
- amino acid
- simultaneous determination
- ms ms
- solid phase extraction
- healthcare
- small molecule
- escherichia coli
- staphylococcus aureus
- electronic health record
- drinking water
- high throughput
- molecular docking
- big data
- high resolution
- fatty acid
- general practice
- data analysis