The Ruminant Telomere-to-Telomere (RT2T) Consortium.
Theodore S KalbfleischStephanie D McKayBrenda M MurdochDavid L AdelsonDiego Almansa-VillaGabrielle M BeckerLinda M BeckettMaría José Benítez-GaleanoFernando BiaseTheresa M CaseyEdward Boyi ChuongEmily ClarkShannon M ClarkeNoelle CockettChristine CouldreyBrian W DavisChristine G ElsikThomas FarautYahui GaoCarine GenetPatrick G S GradyJonathan GreenRichard GreenDai-Lu GuanDarren Erich HagenGabrielle A HartleyMichael P HeatonSavannah J HoytWen HuangErich JarvisJenna KallebergHasan KhatibKlaus-Peter KoepfliJames Eugene KoltesSergey KorenChrista KuehnTosso LeebAlexander S LeonardGeorge E LiuWai Yee LowHunter McConnellKathryn McRaeKaren MigaMichelle MouselHolly NeibergsTemitayo OlagunjuMatt PennellBruna PetryMirjam PewsnerAdam M PhillippyBrandon D PickettPaulene PinedaTamara PotapovaSatyanarayana RachaganiArang RhieMonique RijnkelsAnnie RobicNelida Rodriguez OsorioYana SafonovaGustavo SchettiniRobert D SchnabelNagabhishek Sirpu NateshMorgan R StegemillerJessica StorerPaul StothardCaleb StullGwenola Tosser-KloppGerman Matias TragliaChristopher K TuggleCurtis P Van TassellCorey T WatsonRosemarie WeikardKlaus WimmersShangqian XieLiu YangTimothy P L SmithRachel J O'NeillBenjamin D RosenPublished in: Nature genetics (2024)
Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously 'invisible' parts of the genome and allow comparative analyses of complete genomes across entire clades. We present here an open collaborative effort, termed the 'Ruminant T2T Consortium' (RT2T), that aims to generate complete diploid assemblies for numerous species of the Artiodactyla suborder Ruminantia to examine chromosomal evolution in the context of natural selection and domestication of species used as livestock.