Promotion of epithelial hyperplasia by interleukin-8-CXCR axis in human prostate.

Diandra K SmithSarrah L HasanaliJiaojiao WangGeorgios KallifatidisDaley S MoreraAndre R JordanMartha K TerrisZachary KlaassenRoni BollagVinata B LokeshwarVinata B Lokeshwar

Published in: The Prostate (2020)

The IL-8 axis is a promotor of BPH pathogenesis. Low-dose OA + UA combination inhibits BPH cell growth by inducing autophagy and reducing IL-8 axis expression in BPH-epithelial cells.

Keyphrases

benign prostatic hyperplasia
lower urinary tract symptoms
low dose
prostate cancer
endothelial cells
poor prognosis
cell death
oxidative stress
signaling pathway
knee osteoarthritis
induced pluripotent stem cells
pluripotent stem cells