Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis.
Ya YangYanfei ChenYalei ZhaoFeiyang JiLingjian ZhangShima TangSainan ZhangQingqing HuZuhong LiFen ZhangQian LiLan-Juan LiPublished in: Stem cell research & therapy (2022)
MenSC transplantation could be an effective treatment method for cholestatic liver injury in mice. MenSCs may exhibit therapeutic effects by regulating β-catenin expression.
Keyphrases
- liver injury
- drug induced
- stem cell transplantation
- high dose
- endothelial cells
- poor prognosis
- cell proliferation
- signaling pathway
- epithelial mesenchymal transition
- induced pluripotent stem cells
- high glucose
- high fat diet induced
- low dose
- type diabetes
- pluripotent stem cells
- cell therapy
- binding protein
- combination therapy
- metabolic syndrome
- insulin resistance