SIGLEC1 (CD169) is a sensitive biomarker for the deterioration of the clinical course in childhood systemic lupus erythematosus.

Sae Lim von StuckradJens KlotscheRobert BiesenMareike LieberJulia ThumfartChristian MeiselNadine UnterwalderTilmann Kallinich

Published in: Lupus (2020)

SIGLEC1 expression on monocytes is a sensitive biomarker for adjusting disease activity in childhood SLE and represents a promising and easily applicable tool for disease monitoring.

Keyphrases

disease activity
systemic lupus erythematosus
rheumatoid arthritis patients
rheumatoid arthritis
ankylosing spondylitis
juvenile idiopathic arthritis
poor prognosis
early life
childhood cancer
dendritic cells
peripheral blood
young adults
binding protein