Highlights from Studies Presented at the Virtual American College of Cardiology Scientific Sessions 2021: Staying Updated with the Latest Advancements in Prevention.
Vardhmaan JainMahmoud Al RifaiDhruv MahttaJing LiuAliza HussainSalim S ViraniPublished in: Current atherosclerosis reports (2021)
The studies reviewed include clinical trials that assessed the use of dapagliflozin in patients with respiratory failure due to COVID-19 (DARE-19 trial); evinacumab for patients with severe hypertriglyceridemia and pancreatitis; effect of genotype-guided oral P2y12 inhibitors vs conventional clopidogrel on long-term ischemic outcomes after percutaneous coronary intervention (TAILOR-PCI trial); anticoagulation in patients hospitalized with COVID-19 (ACTION trial); atorvastatin vs placebo in patients with COVID-19 admitted to the ICU (INSPIRATION-S trial); rehabilitation therapy in older acute heart failure patients (REHAB-HF trial); and aspirin dosing: a patient-centric trial assessing benefits and long-term effectiveness (ADAPTABLE trial). In addition, we review the results of the American College of Cardiology Global Heart Attack Initiative (GHATI). Finally, we discuss the secondary analysis of the STRENGTH trial assessing the association of achieved levels of omega-3 fatty acid levels and major cardiovascular outcomes. The studies presented at the virtual American College of Cardiology Scientific Session 2021 represent remarkable contributions in the field of cardiovascular disease and prevention.
Keyphrases
- phase iii
- clinical trial
- study protocol
- phase ii
- percutaneous coronary intervention
- cardiovascular disease
- respiratory failure
- randomized controlled trial
- coronavirus disease
- acute coronary syndrome
- sars cov
- atrial fibrillation
- systematic review
- antiplatelet therapy
- stem cells
- heart failure
- ejection fraction
- intensive care unit
- fatty acid
- early onset
- coronary artery disease
- extracorporeal membrane oxygenation
- liver failure
- physical activity
- acute kidney injury
- st segment elevation myocardial infarction
- coronary artery bypass grafting
- cardiovascular events
- venous thromboembolism
- smoking cessation
- bone marrow
- cardiovascular risk factors
- working memory
- patient reported outcomes