Utilizing Human-Induced Pluripotent Stem Cells to Study Cardiac Electroporation Pulsed-Field Ablation.

Leonid Maizels Eyal HellerMichal LandesbergShany GlatsteinIrit HuberGil ArbelAmira GepsteinDoron AronsonShirley SharabiRoy BeinartAmit SegevElad Maor Lior Gepstein

Published in: Circulation. Arrhythmia and electrophysiology (2024)

Cardiac electroporation may be studied using hiPSC-derived cardiac tissue, providing novel insights into PFA temporal and electrophysiological characteristics, facilitating electroporation protocol optimization, screening for potential PFA-sensitizers, and investigating the mechanistic nature of PFA antiarrhythmic properties.

Keyphrases

induced pluripotent stem cells
left ventricular
endothelial cells
randomized controlled trial
pluripotent stem cells
radiofrequency ablation
solar cells