In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds.

Michel HaagdorensVytautas CėplaEline MelsbachLaura KoivusaloHeli SkottmanMay GriffithRamūnas ValiokasNadia ZakariaIsabel PintelonMarie-José Tassignon

Published in: Stem cells international (2019)

RHC I and DMTMM-crosslinked CLP hydrogels, irrespective of surface modification, support successful cultivation of primary human LESC using a xeno-free cultivation protocol. The regenerated epithelium maintained similar characteristics to HAM-based cultures.

Keyphrases

stem cells
tissue engineering
hyaluronic acid
endothelial cells
randomized controlled trial
wound healing
drug delivery
induced pluripotent stem cells
pluripotent stem cells
extracellular matrix
drug release
cell therapy
mesenchymal stem cells