Ursodeoxycholic acid attenuates the expression of proinflammatory cytokines in periodontal cells.
Reza TalebianLayla PanahipourReinhard GruberPublished in: Journal of periodontology (2020)
Taken together, UDCA can attenuate the provoked expression of inflammatory cytokines in oral fibroblasts, oral human squamous carcinoma cells and macrophages in vitro. These data support the hypothesis that patients with cholestatic liver disease might benefit from UDCA with respect to periodontal health.
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