Naturally-acquired and Vaccine-induced Human Monoclonal Antibodies to Plasmodium vivax Duffy Binding Protein Inhibit Invasion of Plasmodium knowlesi (PvDBPOR) Transgenic Parasites.
Quentin D WatsonLenore L CariasAlyssa MalachinKarli R RedingerJürgen BoschMartino BardelliRobert William MoonSimon J DraperPeter A ZimmermanChristopher L KingPublished in: bioRxiv : the preprint server for biology (2023)
-based PkPvDBPOR transgenic model system enables efficient assessment of NA and VI humAbs individually and in combination. As such, this model could prioritize specific humAb combinations ahead of clinical trials of these reagents.