Simon J Draper

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 46

Top Topics

Plasmodium Falciparum

Binding Protein

Quality Control

Histone Deacetylase

Top Venues

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Francisco José Martínez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander Singh Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial. NPJ vaccines 9 (1) (2024)
Francisco José Martínez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander Singh Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial. NPJ vaccines 9 (1) (2024)
Barnabas G Williams, Lloyd D W King, David Pulido, Doris Quinkert, Amelia M Lias, Sarah E Silk, Robert J Ragotte, Hannah Davies, Jordan R Barrett, Kirsty McHugh, Cassandra A Rigby, Daniel G W Alanine, Lea K Barfod, Michael W Shea, Li An Cowley, Rebecca A Dabbs, David J Pattinson, Alexander D Douglas, Oliver R Lyth, Joseph J Illingworth, Jing Jin, Cecilia Carnrot, Vinayaka Kotraiah, Jayne M Christen, Amy R Noe, Randall S MacGill, C Richter King, Ashley J Birkett, Lorraine A Soisson, Katherine Skinner, Kazutoyo Miura, Carole A Long, Matthew K Higgins, Simon J Draper
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex. Nature communications 15 (1) (2024)
Barnabas G Williams, Lloyd D W King, David Pulido, Doris Quinkert, Amelia M Lias, Sarah E Silk, Robert J Ragotte, Hannah Davies, Jordan R Barrett, Kirsty McHugh, Cassandra A Rigby, Daniel G W Alanine, Lea K Barfod, Michael W Shea, Li An Cowley, Rebecca A Dabbs, David J Pattinson, Alexander D Douglas, Oliver R Lyth, Joseph J Illingworth, Jing Jin, Cecilia Carnrot, Vinayaka Kotraiah, Jayne M Christen, Amy R Noe, Randall S MacGill, C Richter King, Ashley J Birkett, Lorraine A Soisson, Katherine Skinner, Kazutoyo Miura, Carole A Long, Matthew K Higgins, Simon J Draper
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex. Nature communications 15 (1) (2024)
Thomas E Harrison, Nawsad Alam, Brendan Farrell, Doris Quinkert, Amelia M Lias, Lloyd D W King, Lea K Barfod, Simon J Draper, Ivan Campeotto, Matthew K Higgins
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5. EMBO molecular medicine (2024)
Barnabas G Williams, Lloyd D W King, David Pulido, Doris Quinkert, Amelia M Lias, Sarah E Silk, Robert J Ragotte, Hannah Davies, Jordan R Barrett, Kirsty McHugh, Cassandra A Rigby, Daniel G W Alanine, Lea K Barfod, Michael W Shea, Li An Cowley, Rebecca A Dabbs, David J Pattinson, Alexander D Douglas, Oliver R Lyth, Joseph J Illingworth, Jing Jin, Cecilia Carnrot, Vinayaka Kotraiah, Jayne M Christen, Amy R Noe, Randall S MacGill, C Richter King, Ashley J Birkett, Lorraine A Soisson, Katherine Skinner, Kazutoyo Miura, Carole A Long, Matthew K Higgins, Simon J Draper
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex. Nature communications 15 (1) (2024)
Francisco José Martínez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander Singh Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial. NPJ vaccines 9 (1) (2024)
Barnabas G Williams, Lloyd D W King, David Pulido, Doris Quinkert, Amelia M Lias, Sarah E Silk, Robert J Ragotte, Hannah Davies, Jordan R Barrett, Kirsty McHugh, Cassandra A Rigby, Daniel G W Alanine, Lea K Barfod, Michael W Shea, Li An Cowley, Rebecca A Dabbs, David J Pattinson, Alexander D Douglas, Oliver R Lyth, Joseph J Illingworth, Jing Jin, Cecilia Carnrot, Vinayaka Kotraiah, Jayne M Christen, Amy R Noe, Randall S MacGill, C Richter King, Ashley J Birkett, Lorraine A Soisson, Katherine Skinner, Kazutoyo Miura, Carole A Long, Matthew K Higgins, Simon J Draper
Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex. Nature communications 15 (1) (2024)
Francisco José Martínez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander Singh Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial. NPJ vaccines 9 (1) (2024)
Francisco José Martínez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M Hou, Sarah E Silk, Jordan R Barrett, Carolyn M Nielsen, Jenny M Reimer, Paushali Mukherjee, Virander Singh Chauhan, Angela M Minassian, Simon J Draper, Chetan E Chitnis
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial. NPJ vaccines 9 (1) (2024)
Quentin D Watson, Lenore L Carias, Alyssa Malachin, Karli R Redinger, Jürgen Bosch, Martino Bardelli, Robert William Moon, Simon J Draper, Peter A Zimmerman, Christopher L King
Naturally-acquired and Vaccine-induced Human Monoclonal Antibodies to Plasmodium vivax Duffy Binding Protein Inhibit Invasion of Plasmodium knowlesi (PvDBPOR) Transgenic Parasites. bioRxiv : the preprint server for biology (2023)
Mimi M Hou, Jordan R Barrett, Yrene Themistocleous, Thomas A Rawlinson, Ababacar Diouf, Francisco José Martínez, Carolyn M Nielsen, Amelia M Lias, Lloyd D W King, Nick J Edwards, Nicola M Greenwood, Lucy Kingham, Ian D Poulton, Baktash Khozoee, Cyndi G Geoghegan, Susanne H Hodgson, Dylan J Mac Lochlainn, Jo Salkeld, Micheline Guillotte-Blisnick, Christèle Huon, Franziska Mohring, Jenny M Reimer, Virander S Chauhan, Paushali Mukherjee, Sumi Biswas, Iona J Brian, Alison M Lawrie, Jee-Sun Cho, Fay L Nugent, Carole A Long, Robert William Moon, Kazutoyo Miura, Sarah E Silk, Chetan E Chitnis, Angela M Minassian, Simon J Draper
Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection. Science translational medicine 15 (704) (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 (7995) (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 (7995) (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 (7995) (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 (7995) (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 (7995) (2023)
Abhishek Jamwal, Cristina F Constantin, Stephan Hirshi, Sebastian Henrich, Wolfgang Bildl, Bernd Fakler, Simon J Draper, Uwe Schulte, Matthew K Higgins
Erythrocyte invasion-neutralising antibodies prevent Plasmodium falciparum RH5 from binding to basigin-containing membrane protein complexes. eLife 12 (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature (2023)
Elena Mitsi, Mariana O Diniz, Jesús Reiné, Andrea M Collins, Ryan E Robinson, Angela Hyder-Wright, Madlen Farrar, Konstantinos Liatsikos, Joshua Hamilton, Onyia Onyema, Britta C Urban, Carla Solórzano, Sandra Belij-Rammerstorfer, Emma Sheehan, Teresa Lambe, Simon J Draper, Daniela Weiskopf, Alessandro Sette, Mala K Maini, Daniela M Ferreira
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination. Nature communications 14 (1) (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 (7995) (2023)
Brendan Farrell, Nawsad Alam, Melissa N Hart, Abhishek Jamwal, Robert J Ragotte, Hannah Walters-Morgan, Simon J Draper, Ellen Knuepfer, Matthew K Higgins
The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature 625 (7995) (2023)
Robert J Ragotte, David Pulido, Amelia M Lias, Doris Quinkert, Daniel G W Alanine, Abhishek Jamwal, Hannah Davies, Adéla Nacer, Edward D Lowe, Geoffrey W Grime, Joseph J Illingworth, Robert F Donat, Elspeth F Garman, Paul W Bowyer, Matthew K Higgins, Simon J Draper
Heterotypic interactions drive antibody synergy against a malaria vaccine candidate. Nature communications 13 (1) (2022)
Mimi M Hou, Jordan R Barrett, Yrene Themistocleous, Thomas A Rawlinson, Ababacar Diouf, Francisco J Martinez, Carolyn M Nielsen, Amelia M Lias, Lloyd D W King, Nick J Edwards, Nicola M Greenwood, Lucy Kingham, Ian D Poulton, Baktash Khozoee, Cyndi G Geoghegan, Dylan J Mac Lochlainn, Jo Salkeld, Micheline Guilotte-Blisnick, Christèle Huon, Franziska Mohring, Jenny M Reimer, Virander Singh Chauhan, Paushali Mukherjee, Sumi Biswas, Iona J Brian, Alison M Lawrie, Jee-Sun Cho, Fay L Nugent, Carole A Long, Robert William Moon, Kazutoyo Miura, Sarah E Silk, Chetan E Chitnis, Angela M Minassian, Simon J Draper
Impact of a blood-stage vaccine on Plasmodium vivax malaria. medRxiv : the preprint server for health sciences (2022)
Olivia Flynn, Kate Dillane, Juliane Sousa Lanza, Jennifer M Marshall, Jing Jin, Sarah E Silk, Simon J Draper, Anne C Moore
Low Adenovirus Vaccine Doses Administered to Skin Using Microneedle Patches Induce Better Functional Antibody Immunogenicity as Compared to Systemic Injection. Vaccines 9 (3) (2021)
Katja Müller, Matthew P Gibbins, Mark Roberts, Arturo Reyes-Sandoval, Adrian V S Hill, Simon J Draper, Kai Matuschewski, Olivier Silvie, Julius Clemence R Hafalla
Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination. EMBO molecular medicine 13 (4) (2021)
Kathryn Milne, Alasdair Ivens, Adam J Reid, Magda E Lotkowska, Aine O'Toole, Geetha Sankaranarayanan, Diana Munoz Sandoval, Wiebke Nahrendorf, Clement Regnault, Nick J Edwards, Sarah E Silk, Ruth O Payne, Angela M Minassian, Navin Venkatraman, Mandy J Sanders, Adrian Vs Hill, Michael Barrett, Matthew Berriman, Simon J Draper, J Alexandra Rowe, Philip J Spence
Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum. eLife 10 (2021)
Danai Papakonstantinou, Steven J Dunn, Simon J Draper, Adam F Cunningham, Matthew K O'Shea, Alan McNally
Mapping Gene-by-Gene Single-Nucleotide Variation in 8,535 Mycobacterium tuberculosis Genomes: a Resource To Support Potential Vaccine and Drug Development. mSphere 6 (2) (2021)
Ivan Campeotto, Francis Galaway, Shahid Mehmood, Lea K Barfod, Doris Quinkert, Vinayaka Kotraiah, Timothy W Phares, Katherine E Wright, Ambrosius P Snijders, Simon J Draper, Matthew K Higgins, Gavin J Wright
The Structure of the Cysteine-Rich Domain of Plasmodium falciparum P113 Identifies the Location of the RH5 Binding Site. mBio 11 (5) (2020)
Rolle Rahikainen, Pramila Rijal, Tiong Kit Tan, Hung-Jen Wu, Anne-Marie C Andersson, Jordan R Barrett, Thomas A Bowden, Simon J Draper, Alain R Townsend, Mark R Howarth
Overcoming Symmetry Mismatch in Vaccine Nanoassembly through Spontaneous Amidation. Angewandte Chemie (International ed. in English) 60 (1) (2020)
Rolle Rahikainen, Pramila Rijal, Tiong Kit Tan, Hung-Jen Wu, Anne-Marie C Andersson, Jordan R Barrett, Thomas A Bowden, Simon J Draper, Alain R Townsend, Mark R Howarth
Overcoming Symmetry Mismatch in Vaccine Nanoassembly through Spontaneous Amidation. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 133 (1) (2020)
Rebecca S Dookie, Ana Villegas-Mendez, Hans Kroeze, Jordan R Barrett, Simon J Draper, Blandine M Franke-Fayard, Chris J Janse, Andrew S MacDonald, Kevin N Couper
Combinatorial Tim-3 and PD-1 activity sustains antigen-specific Th1 cell numbers during blood-stage malaria. Parasite immunology 42 (9) (2020)
Rolle Rahikainen, Pramila Rijal, Tiong Kit Tan, Hung-Jen Wu, Anne-Marie C Andersson, Jordan R Barrett, Thomas A Bowden, Simon J Draper, Alain R Townsend, Mark R Howarth
Overcoming Symmetry Mismatch in Vaccine Nanoassembly through Spontaneous Amidation. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 133 (1) (2020)
Thomas A Rawlinson, Natalie M Barber, Franziska Mohring, Jee Sun Cho, Varakorn Kosaisavee, Samuel F Gérard, Daniel G W Alanine, Geneviève M Labbé, Sean C Elias, Sarah E Silk, Doris Quinkert, Jing Jin, Jennifer M Marshall, Ruth O Payne, Angela M Minassian, Bruce Russell, Laurent Rénia, Francois H Nosten, Robert William Moon, Matthew K Higgins, Simon J Draper
Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody. Nature microbiology 4 (9) (2019)
Shira Warszawski, Elya Dekel, Ivan Campeotto, Jennifer M Marshall, Katherine E Wright, Oliver Lyth, Orli Knop, Neta Regev-Rudzki, Matthew K Higgins, Simon J Draper, Jake Baum, Sarel Jacob Fleishman
Design of a basigin-mimicking inhibitor targeting the malaria invasion protein RH5. Proteins 88 (1) (2019)
Alexander D Douglas, G Christian Baldeviano, Jing Jin, Kazutoyo Miura, Ababacar Diouf, Zenon A Zenonos, Julio A Ventocilla, Sarah E Silk, Jennifer M Marshall, Daniel G W Alanine, Chuan Wang, Nick J Edwards, Karina P Leiva, Luis A Gomez-Puerta, Carmen M Lucas, Gavin J Wright, Carole A Long, Joseph M Royal, Simon J Draper
A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates. Nature communications 10 (1) (2019)
Ellen Knuepfer, Katherine E Wright, Surendra Kumar Prajapati, Thomas A Rawlinson, Franziska Mohring, Marion Koch, Oliver R Lyth, Steven A Howell, Elizabeth Villasis, Ambrosius P Snijders, Robert William Moon, Simon J Draper, Anna Rosanas-Urgell, Matthew K Higgins, Jake Baum, Anthony A Holder
Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites. PLoS pathogens 15 (6) (2019)
Franziska Mohring, Melissa Natalie Hart, Thomas A Rawlinson, Ryan Henrici, James A Charleston, Ernest Diez Benavente, Avnish Patel, Joanna Hall, Neil Almond, Susana Campino, Taane Gregory Clark, Colin J Sutherland, David A Baker, Simon J Draper, Robert William Moon
Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research. eLife 8 (2019)
Anne-Marie C Andersson, Can M Buldun, David J Pattinson, Simon J Draper, Mark Howarth
SnoopLigase peptide-peptide conjugation enables modular vaccine assembly. Scientific reports 9 (1) (2019)
Geneviève M Labbé, Kazutoyo Miura, Sarah E Silk, Wenjuan Gu, James E Moon, Jing Jin, Ruth O Payne, Michael P Fay, Sheetij Dutta, Carole A Long, Simon J Draper
Harmonization study between three laboratories for expression of malaria vaccine clinical trial IgG antibody ELISA data in µg/mL. Malaria journal 18 (1) (2019)
Jing Jin, Richard D Tarrant, Emma J Bolam, Philip Angell-Manning, Max Soegaard, David J Pattinson, Pawan Dulal, Sarah E Silk, Jennifer M Marshall, Rebecca A Dabbs, Fay L Nugent, Jordan R Barrett, Kathryn A Hjerrild, Lars Poulsen, Thomas Jørgensen, Tanja Brenner, Ioana N Baleanu, Helena M Parracho, Abdessamad Tahiri-Alaoui, Gary Whale, Sarah Moyle, Ruth O Payne, Angela M Minassian, Matthew K Higgins, Frank J Detmers, Alison M Lawrie, Alexander D Douglas, Robert Smith, Willem A de Jongh, Eleanor Berrie, Rebecca Ashfield, Simon J Draper
Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells. NPJ vaccines 3 (2018)
João Arezes, Niall Foy, Kirsty McHugh, Anagha Sawant, Doris Quinkert, Virginie Terraube, Alette Brinth, May Tam, Edward R LaVallie, Stephen Taylor, Andrew E Armitage, Sant-Rayn Pasricha, Orla Cunningham, Matthew Lambert, Simon J Draper, Reema Jasuja, Hal Drakesmith
Erythroferrone inhibits the induction of hepcidin by BMP6. Blood 132 (14) (2018)
Natasha Spottiswoode, Andrew E Armitage, Andrew R Williams, Alex J Fyfe, Sumi Biswas, Susanne H Hodgson, David Llewellyn, Prateek Choudhary, Simon J Draper, Patrick E Duffy, Hal Drakesmith
Role of Activins in Hepcidin Regulation during Malaria. Infection and immunity 85 (12) (2017)
Ivan Campeotto, Adi Goldenzweig, Jack Davey, Lea Barfod, Jennifer M Marshall, Sarah E Silk, Katherine E Wright, Simon J Draper, Matthew K Higgins, Sarel J Fleishman
One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen. Proceedings of the National Academy of Sciences of the United States of America 114 (5) (2017)
Sant-Rayn Pasricha, Pei Jin Lim, Tiago L Duarte, Carla Casu, Dorenda Oosterhuis, Katarzyna Mleczko-Sanecka, Maria Suciu, Ana Rita Da Silva, Kinda Al-Hourani, João Arezes, Kirsty McHugh, Sarah Gooding, Joe N Frost, Katherine Wray, Ana Santos, Graça Porto, Emmanouela Repapi, Nicki Gray, Simon J Draper, Neil Ashley, Elizabeth Soilleux, Peter Olinga, Martina U Muckenthaler, Jim R Hughes, Stefano Rivella, Thomas A Milne, Andrew E Armitage, Hal Drakesmith
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3. Nature communications 8 (1) (2017)
Chuan Wang, Matthew Hart, Cecilia Chui, Augustine Ajuogu, Iona J Brian, Simone C de Cassan, Persephone Borrow, Simon J Draper, Alexander D Douglas
Germinal Center B Cell and T Follicular Helper Cell Responses to Viral Vector and Protein-in-Adjuvant Vaccines. Journal of immunology (Baltimore, Md. : 1950) 197 (4) (2016)