The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing.

Irene Y ChongNaureen StarlingAlistair RustJohn AlexanderLauren I AronsonMarta Llorca-CardenosaRitika ChauhanAsif ChaudrySacheen KumarKerry FenwickIoannis AssiotisNik MatthewsRuwaida BegumAndrew WotherspoonMonica TerlizzoDavid WatkinsIan ChauChristopher J LordSyed HaiderSheela RaoDavid Cunningham

Published in: Journal of clinical medicine (2021)

These data suggest that comprehensive genomic data can be generated from exome sequencing of selected DNA samples extracted from archival FFPE gastro-oesophageal tumour tissues within the context of prospective clinical trials.

Keyphrases

clinical trial
electronic health record
copy number
big data
gene expression
circulating tumor
cell free
machine learning
randomized controlled trial
deep learning