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The Intestinal Microbiota and Short-Chain Fatty Acids in Association with Advanced Metrics of Glycemia and Adiposity Among Young Adults with Type 1 Diabetes and Overweight or Obesity.

Daria IgudesmanJamie CrandellKaren D CorbinFranklin MuntisDessi P ZaharievaAnna CasuJoan M ThomasCynthia M BulikIan M CarrollBrian W PenceRichard E PratleyMichael R KosorokDavid M MaahsElizabeth J Mayer-Davis
Published in: Current developments in nutrition (2022)
Unexpectedly, fecal propionate was associated with detriment to glycemia, whereas most SCFA-producing intestinal microbes were associated with benefit to adiposity. Future studies should confirm these associations and determine their potential causal linkages in T1D.This study is registered at clinical.trials.gov (NCT03651622; https://clinicaltrials.gov/ct2/show/NCT03651622).
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