The clinical and pathological effectiveness of microneedling and topical 5-fluorouracil in vitiligo treatment: An association with matrix metalloproteinase 2 immunohistochemical expression.

Asmaa Gaber AbdouAzza Gaber Antar FaragManal RashwanWafaa Ahmed Shehata

Published in: Journal of cosmetic dermatology (2021)

5-Fluorouracil application after microneedling is effective in the treatment of vitiligo with 75% response, 60% patient satisfaction, and tolerable side effects. The improvement in vitiligo patients by microneedling and 5-fluorouracil could be due to upregulation of MMP2 in affected vitiligo specimens.

Keyphrases

patient satisfaction
poor prognosis
end stage renal disease
randomized controlled trial
systematic review
ejection fraction
prognostic factors
peritoneal dialysis
cell migration
patient reported