Collagen Remodeling and Fatty Acid Regulation Biomarkers in Understanding the Molecular Pathogenesis of Atrial Fibrillation.
Ameer OdehGabriel D DunganAmir DarkiDebra Moorman HoppensteadtFakiha SiddiquiBulent KantarciogluJawed FareedMushabbar A SyedPublished in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2022)
The elevation of collagen remodeling biomarkers suggests an upregulation of these biomarkers and their potential role in AF, which may contribute to atrial fibrosis. L-FABP and NEFAs were elevated in AF patients. The correlations between the collagen remodeling and fatty acid dysregulation biomarkers may be due to their involvement in structural remodeling of the atria.
Keyphrases
- atrial fibrillation
- fatty acid
- end stage renal disease
- left atrial
- catheter ablation
- ejection fraction
- chronic kidney disease
- heart failure
- oral anticoagulants
- cell proliferation
- left atrial appendage
- wound healing
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- tissue engineering
- poor prognosis
- binding protein
- percutaneous coronary intervention
- left ventricular
- venous thromboembolism
- acute coronary syndrome
- mitral valve
- patient reported