Up regulation of long non-coding RNAs BACE1 and down regulation of LINC-PINT are associated with CRC clinicopathological characteristics.

Sara Bakhtiari-NezhadLeili RejaliMahrooyeh HadizadehMohammad Yaghob TaleghaniHamid Asadzadeh AghdaeiChris YoungBinazir KhanabadiEhsan Nazemalhosseini-MojaradMaziar Ashrafian Bonab

Published in: Molecular biology reports (2022)

We investigated two LNCRNAs (PINT and BACE1) as potential CRC prognostic biomarkers, which are imperative for early and effective medical intervention in CRC. Expression levels of PINT and BACE1 in CRC tissue samples may serve to identify metastasis earlier, increasing patient survival rates and expediating clinical treatment options.

Keyphrases

long non coding rna
poor prognosis
randomized controlled trial
healthcare
case report
cell proliferation
atomic force microscopy
human health