Standard pancreatoduodenectomy versus extended pancreatoduodenectomy with modified retroperitoneal nerve resection in patients with pancreatic head cancer: a multicenter randomized controlled trial.
Qing LinShangyou ZhengXian-Jun YuMeifu ChenYu ZhouQuanbo ZhouChonghui HuJing GuZhongdong XuLin WangYimin LiuQingyu LiuMin WangGuolin LiHe ChengDongkai ZhouGuodong LiuZhiqiang FuYu LongYixiong LiWeilin WangRenyi QinZhihua LiRufu ChenPublished in: Cancer communications (London, England) (2022)
EPD for pancreatic head cancer did not significantly improve OS, but patients with EPD treatment had significantly improved DFS. In the subgroup analysis, improvements in both OS and DFS in the EPD arm were observed in patients with preoperative CA19-9 < 200.0 U/mL. EPD could be used as an effective surgical procedure for patients with pancreatic head cancer, especially those with preoperative CA19-9 < 200.0 U/mL.