Plastic induced urinary tract disease and dysfunction: a scoping review.
Liam O'CallaghanMatthew OlsenLotti TajouriDavinia BeaverCarly HudsonRashed AlghafriSimon J McKirdyAdrian GoldsworthyPublished in: Journal of exposure science & environmental epidemiology (2024)
This scoping review highlights the rapidly emerging threat of microplastic contamination within the human urinary tract, challenging the World Health Organisation's assertion that microplastics pose no risk to public health. The documented cytotoxic effects of microplastics, alongside their ability to induce inflammation, reduce cell viability and disrupt signalling pathways, raise significant public health concerns relating to bladder cancer, chronic kidney disease, chronic urinary tract infections and incontinence. As a result, this study emphasises the pressing need for further research and policy development to address the challenges surrounding microplastic contamination.
Keyphrases
- public health
- urinary tract
- urinary tract infection
- human health
- chronic kidney disease
- risk assessment
- oxidative stress
- endothelial cells
- drinking water
- high glucose
- global health
- diabetic rats
- end stage renal disease
- healthcare
- drug induced
- mental health
- climate change
- pluripotent stem cells
- health information
- muscle invasive bladder cancer