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Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis.

Romina Kaveh-AhangaranMohammad AbdollahiMohammad VaeziAmir KasaeianZhalleh BahlouliGhasem JanbabaeeAmirmahdi MojtahedzadehMojtaba MojtahedzadehShirin DjalaliniaBita Shahrami
Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2024)
An oral bicarbonate regimen is a safe and effective way to alkalize HDMTX urine, providing a viable and cost-effective alternative to IV protocols. Further prospective multicenter studies are necessary. Systematic review registration identifier: CRD42023379666.
Keyphrases
  • high dose
  • systematic review
  • low dose
  • stem cell transplantation
  • meta analyses
  • randomized controlled trial
  • clinical trial
  • cross sectional