European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease-the substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow.

Olga MeulenbroekSarah O'DwyerDaan de JongGerrita van SpijkerSean KennellyFiona CreggMarcel Olde RikkertLaila AbdullahAnders WallinCathal WalshRobert CoenRose Anne KennyLeslie DalyRicardo SeguradoAnne Borjesson-HansonFiona CrawfordMichael MullanUgo LuccaRita BanziFlorence PasquierLaetitia BreuilhMatthias RiepeJanos KalmanDavid William MolloyMagda TsolakiRobert HowardJessica AdamsSiobhan GaynorBrian Lawlor

Published in: BMJ open (2016)

EUDRACT 2012-002764-27; Pre-results.

Keyphrases

double blind
cerebral blood flow
cerebrospinal fluid
placebo controlled
clinical trial
study protocol
phase iii
cognitive decline
randomized controlled trial
copy number
cross sectional
gene expression