The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models.
Shoshy A BrinchEnya Amundsen-IsaksenSandra EspadaClara HammarströmAleksandra AizenshtadtPetter Angell OlsenLone HolmenMerete HøyemHanne ScholzGunnveig GrødelandSven T SowaAlbert Galera-PratLari LehtiöIlonka A T M MeertsRuben G G LeendersAnita WegertStefan KraussJo WaalerPublished in: Cancer research communications (2022)
This study uncovers the effectiveness and therapeutic window for a novel tankyrase inhibitor in mouse tumor models.