Direct Oral Anticoagulants Versus Warfarin in the Treatment of Cerebral Venous Thrombosis (ACTION-CVT): A Multicenter International Study.
Shadi YaghiLiqi ShuEkaterina BakradzeSetareh Salehi OmranJames A GilesJordan Y AmarNils HenningerMarwa ElnazeirAva L LibermanKhadean MoncrieffeJenny LuRicha SharmaYee ChengAdeel S ZubairAlexis N SimpkinsGrace T LiJustin Chi KungDezaray PerezMirjam Rachel HeldnerAdrian ScutelnicDavid Julian SeiffgeBernhard SiepenAaron RothsteinOssama KhazaalDavid DoSami Al KasabLine Abdul RahmanEva A MistryDeborah KerriganHayden LafeverThanh N NguyenPiers KleinHugo Javier AparicioJennifer A FronteraLindsey R KuohnShashank AgarwalChristoph StretzNarendra KalaSleiman El JamalAlison ChangShawna CuttingHan XiaoAdam H de HavenonVarsha MuddasaniTeddy Y WuDuncan WilsonAmre NouhSyed Daniyal AsadAbid Y QureshiJustin MoorePooja KhatriYasmin Ninette AzizBryce CasteigneMuhib KhanYao ChengBrian Mac GroryMartin WeissDylan RyanMaria Cristina VedovatiMaurizio PaciaroniJames E SieglerScott KamenSiyuan YuChristopher R Leon GuerreroEugenie AtallahGian Marco De MarchisBrehm AlexTolga Daniel DittrichMarios-Nikos PsychogiosRonald Alvarado-DyerTareq Kass-HoutShyam PrabhakaranTristan HondaDavid S LiebeskindKaren L FuriePublished in: Stroke (2022)
In patients with CVT, treatment with DOACs was associated with similar clinical and radiographic outcomes and favorable safety profile when compared with warfarin treatment. Our findings need confirmation by large prospective or randomized studies.