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Establishment of oxaliplatin-resistant gastric cancer organoids: importance of myoferlin in the acquisition of oxaliplatin resistance.

Kenji HaradaNaoya SakamotoShoichi UkaiYusuke YamamotoQuoc Thang PhamDaiki TaniyamaRirino HonmaRyota MaruyamaTsuyoshi TakashimaHiroshi OtaYuki TakemotoKazuaki TanabeHideki OhdanWataru Yasui
Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2021)
Our results suggest that MYOF is highly involved in L-OHP resistance and tumor progression in GC. MYOF could be a promising biomarker and therapeutic target for L-OHP-resistant GC cases.
Keyphrases
  • poor prognosis
  • pluripotent stem cells