Long-term inorganic nitrate administration protects against myocardial ischemia-reperfusion injury in female rats.
Younes YassaghiSajad JeddiNasibeh YousefzadehKhosrow KashfiAsghar GhasemiPublished in: BMC cardiovascular disorders (2023)
Long-term nitrate intervention increased the resistance to MIRI in female rats; this was associated with increased heart eNOS expression and circulating progesterone before ischemia and blunting ischemia-induced increased iNOS and decreased eNOS after MIRI.