Individualized positive end-expiratory pressure guided by end-expiratory lung volume in early acute respiratory distress syndrome: study protocol for the multicenter, randomized IPERPEEP trial.

Domenico Luca GriecoSalvatore Maurizio MaggioreGiacomo BellaniSavino SpadaroElena SpinelliTommaso TonettiLuca S MengaMarco PozziDenise BattagliniRosa Di MussiAndrea BruniAndrea De GaetanoCarmine Giovanni IovinoMatteo BrioniFrancesco MojoliGiuseppe FotiCarlo Aberto VoltaPaolo PelosiPaolo NavalesiSalvatore GrassoV Marco RanieriMassimo Antonellinull null

Published in: Trials (2022)

ClinicalTrials.gov NCT04012073 . Registered 9 July 2019.

Keyphrases

acute respiratory distress syndrome
mechanical ventilation
phase iii
double blind
extracorporeal membrane oxygenation
phase ii
open label
clinical trial
placebo controlled
study protocol
intensive care unit
cross sectional
randomized controlled trial