The expression and clinical significance of ERβ/ERα in ovarian cancer: can we predict the effectiveness of platinum plus taxane therapy?
Tatiana A BogushAnna A BasharinaElena A BogushAlexander M ScherbakovMikhail M DavydovVyacheslav S KosorukovPublished in: Irish journal of medical science (2021)
A high level of ERβ and not ERα expression can predict the efficacy of front-line platinum plus taxane chemotherapy in stage III HGSOC patients. The status of estrogen receptor beta can be considered as one of the possible predictors for evaluating the effectiveness of ovarian cancer therapy.
Keyphrases
- estrogen receptor
- poor prognosis
- cancer therapy
- end stage renal disease
- randomized controlled trial
- systematic review
- endoplasmic reticulum
- newly diagnosed
- ejection fraction
- breast cancer cells
- chronic kidney disease
- drug delivery
- peritoneal dialysis
- binding protein
- squamous cell carcinoma
- radiation therapy
- patient reported outcomes
- locally advanced
- cell therapy