Sustained Minimal Residual Disease Negativity in Multiple Myeloma is Associated with Stool Butyrate and Healthier Plant-Based Diets.
Urvi A ShahKylee H MaclachlanAndriy DerkachMeghan SalcedoKelly BarnettJulia CapleJenna BlaslovLinh TranAmanda CiardielloMiranda BurgeTala ShekarkhandPeter A AdintoriJustin R CrossMatthew J PiankoKinga K HosszuDevin McAvoySham MailankodyNeha KordeMalin L HultcrantzHani HassounCarlyn Rose TanSydney X LuDhwani PatelBenjamin T DiamondGunjan L ShahMichael ScordoOscar B LahoudDavid J ChungHeather J LandauSaad Z UsmaniSergio A GiraltYing TaurCarl Ola LandgrenGladys BlockTorin J BlockJonathan U PeledMarcel R M van den BrinkAlexander M LesokhinPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
This is the first study to demonstrate an association between a plant-based dietary pattern, stool butyrate production, and sustained MRD negativity in multiple myeloma, providing rationale to evaluate a prospective dietary intervention.