Marcel R M van den Brink (Marcel van den Brink, M R M van den Brink)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 80

Top Venues

Nature microbiology

Blood

Cancer immunology research

Nature communications

Memorial Sloan-Kettering Cancer Center

Leiden University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Memorial Sloan-Kettering Cancer Center Mar 01 2008

United States

Head, Division of Hematologic Malignancies :: Medicine

Education History

Leiden University Nov 01 1986 - Oct 01 1991

Netherlands

PHD :: Medicine (Immunology)

Publications

Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes. Nature microbiology 9 (6) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Brandon D Ng, Adhithi Rajagopalan, Anastasia I Kousa, Jacob S Fischman, Sophia Chen, Alyssa Rae Massa, Harold Kunal Elias, Dylan Manuele, Michael Galiano, Andri L Lemarquis, Alexander P Boardman, Susan DeWolf, Jonah Addison Pierce, Bjarne Bogen, Scott E James, Marcel R M van den Brink
IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model. Blood 144 (2) (2024)
Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes. Nature microbiology 9 (6) (2024)
Brandon D Ng, Adhithi Rajagopalan, Anastasia I Kousa, Jacob S Fischman, Sophia Chen, Alyssa Rae Massa, Harold Kunal Elias, Dylan Manuele, Michael Galiano, Andri L Lemarquis, Alexander P Boardman, Susan DeWolf, Jonah Addison Pierce, Bjarne Bogen, Scott E James, Marcel R M van den Brink
IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model. Blood 144 (2) (2024)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-Related Colitis Is Associated with Fecal Microbial Dysbiosis and Can Be Mitigated by Fecal Microbiota Transplantation. Cancer immunology research 12 (3) (2024)
Anastasia I Kousa, Lorenz Jahn, Kelin Zhao, Angel E Flores, Dante Acenas, Emma Lederer, Kimon V Argyropoulos, Andri L Lemarquis, David Granadier, Kirsten Cooper, Michael D'Andrea, Julie M Sheridan, Jennifer J Tsai, Lisa Sikkema, Amina Lazrak, Katherine Nichols, Nichole Lee, Romina Ghale, Florent Malard, Hana Andrlova, Enrico Velardi, Salma Youssef, Marina Burgos da Silva, Melissa Docampo, Roshan Sharma, Linas Mazutis, Verena C Wimmer, Kelly L Rogers, Susan DeWolf, Brianna Gipson, Antonio L C Gomes, Manu Setty, Dana Pe'er, Laura Hale, Nancy R Manley, Daniel H D Gray, Marcel R M van den Brink, Jarrod A Dudakov
Age-related epithelial defects limit thymic function and regeneration. Nature immunology (2024)
Pedro H V Saavedra, Alissa J Trzeciak, Allie Lipshutz, Andrew W Daman, Anya J O' Neal, Zong-Lin Liu, Zhaoquan Wang, Jesús E Romero-Pichardo, Waleska Saitz Rojas, Giulia Zago, Marcel R M van den Brink, Steven Z Josefowicz, Christopher D Lucas, Christopher J Anderson, Alexander Y Rudensky, Justin S A Perry
Broad-spectrum antibiotics disrupt homeostatic efferocytosis. Nature metabolism (2024)
Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes. Nature microbiology (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Pedro H V Saavedra, Alissa J Trzeciak, Allie Lipshutz, Andrew W Daman, Anya J O' Neal, Zong-Lin Liu, Zhaoquan Wang, Jesús E Romero-Pichardo, Waleska Saitz Rojas, Giulia Zago, Marcel R M van den Brink, Steven Z Josefowicz, Christopher D Lucas, Christopher J Anderson, Alexander Y Rudensky, Justin S A Perry
Broad-spectrum antibiotics disrupt homeostatic efferocytosis. Nature metabolism (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer (2024)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-Related Colitis Is Associated with Fecal Microbial Dysbiosis and Can Be Mitigated by Fecal Microbiota Transplantation. Cancer immunology research 12 (3) (2024)
Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes. Nature microbiology (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer (2024)
Yongxian Hu, Jingjing Li, Fang Ni, Zhongli Yang, Xiaohua Gui, Zhiwei Bao, Houli Zhao, Guoqing Wei, Yiyun Wang, Mingming Zhang, Ruimin Hong, Linqin Wang, Wenjun Wu, Mohamad Mohty, Arnon Nagler, Alex H Chang, Marcel R M van den Brink, Ming D Li, He Huang
Author Correction: CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies. Nature communications 15 (1) (2024)
Brandon D Ng, Adhithi Rajagopalan, Anastasia I Kousa, Jacob S Fischman, Sophia Chen, Alyssa Rae Massa, Harold Kunal Elias, Dylan Manuele, Michael Galiano, Andri L Lemarquis, Alexander P Boardman, Susan DeWolf, Jonah Addison Pierce, Bjarne Bogen, Scott E James, Marcel R M van den Brink
IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model. Blood 144 (2) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Anastasia I Kousa, Lorenz Jahn, Kelin Zhao, Angel E Flores, Dante Acenas, Emma Lederer, Kimon V Argyropoulos, Andri L Lemarquis, David Granadier, Kirsten Cooper, Michael D'Andrea, Julie M Sheridan, Jennifer J Tsai, Lisa Sikkema, Amina Lazrak, Katherine Nichols, Nichole Lee, Romina Ghale, Florent Malard, Hana Andrlova, Enrico Velardi, Salma Youssef, Marina Burgos da Silva, Melissa Docampo, Roshan Sharma, Linas Mazutis, Verena C Wimmer, Kelly L Rogers, Susan DeWolf, Brianna Gipson, Antonio L C Gomes, Manu Setty, Dana Pe'er, Laura Hale, Nancy R Manley, Daniel H D Gray, Marcel R M van den Brink, Jarrod A Dudakov
Age-related epithelial defects limit thymic function and regeneration. Nature immunology 25 (9) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Anastasia I Kousa, Lorenz Jahn, Kelin Zhao, Angel E Flores, Dante Acenas, Emma Lederer, Kimon V Argyropoulos, Andri L Lemarquis, David Granadier, Kirsten Cooper, Michael D'Andrea, Julie M Sheridan, Jennifer J Tsai, Lisa Sikkema, Amina Lazrak, Katherine Nichols, Nichole Lee, Romina Ghale, Florent Malard, Hana Andrlova, Enrico Velardi, Salma Youssef, Marina Burgos da Silva, Melissa Docampo, Roshan Sharma, Linas Mazutis, Verena C Wimmer, Kelly L Rogers, Susan DeWolf, Brianna Gipson, Antonio L C Gomes, Manu Setty, Dana Pe'er, Laura Hale, Nancy R Manley, Daniel H D Gray, Marcel R M van den Brink, Jarrod A Dudakov
Age-related epithelial defects limit thymic function and regeneration. Nature immunology 25 (9) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes. Nature microbiology (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Anastasia I Kousa, Lorenz Jahn, Kelin Zhao, Angel E Flores, Dante Acenas, Emma Lederer, Kimon V Argyropoulos, Andri L Lemarquis, David Granadier, Kirsten Cooper, Michael D'Andrea, Julie M Sheridan, Jennifer J Tsai, Lisa Sikkema, Amina Lazrak, Katherine Nichols, Nichole Lee, Romina Ghale, Florent Malard, Hana Andrlova, Enrico Velardi, Salma Youssef, Marina Burgos da Silva, Melissa Docampo, Roshan Sharma, Linas Mazutis, Verena C Wimmer, Kelly L Rogers, Susan DeWolf, Brianna Gipson, Antonio L C Gomes, Manu Setty, Dana Pe'er, Laura Hale, Nancy R Manley, Daniel H D Gray, Marcel R M van den Brink, Jarrod A Dudakov
Age-related epithelial defects limit thymic function and regeneration. Nature immunology 25 (9) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Yongxian Hu, Jingjing Li, Fang Ni, Zhongli Yang, Xiaohua Gui, Zhiwei Bao, Houli Zhao, Guoqing Wei, Yiyun Wang, Mingming Zhang, Ruimin Hong, Linqin Wang, Wenjun Wu, Mohamad Mohty, Arnon Nagler, Alex H Chang, Marcel R M van den Brink, Ming D Li, He Huang
Author Correction: CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies. Nature communications 15 (1) (2024)
Sarah Lindner, Oriana Miltiadous, Ruben J F Ramos, Jenny Paredes, Anastasia I Kousa, Anqi Dai, Teng Fei, Emma Lauder, John Frame, Nicholas R Waters, Keimya Sadeghi, Gabriel K Armijo, Romina Ghale, Kristen Victor, Brianna Gipson, Sebastien Monette, Marco Vincenzo Russo, Chi L Nguyen, John Slingerland, Ying Taur, Kate A Markey, Hana Andrlova, Sergio Giralt, Miguel-Ángel Perales, Pavan Reddy, Jonathan U Peled, Melody Smith, Justin R Cross, Marina Burgos da Silva, Clarissa Campbell, Marcel R M van den Brink
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease. Nature microbiology 9 (3) (2024)
Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Jinlong Ru, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sascha Göttert, Sebastian Jarosch, Katja Steiger, Christian Schulz, Michael Gigl, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Juergen Ruland, Marcel R M van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk H Busch, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nature cancer 5 (1) (2024)
Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes. Nature microbiology 9 (6) (2024)
Chen Liao, Thierry Rolling, Ana Djukovic, Teng Fei, Vishwas Mishra, Hongbin Liu, Chloe Lindberg, Lei Dai, Bing Zhai, Jonathan U Peled, Marcel R M van den Brink, Tobias M Hohl, Joao B Xavier
Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes. Nature microbiology (2024)
Brandon D Ng, Adhithi Rajagopalan, Anastasia I Kousa, Jacob S Fischman, Sophia Chen, Alyssa Rae Massa, Harold Kunal Elias, Dylan Manuele, Michael Galiano, Andri L Lemarquis, Alexander P Boardman, Susan DeWolf, Jonah Addison Pierce, Bjarne Bogen, Scott E James, Marcel R M van den Brink
IL-18-secreting multiantigen targeting CAR T cells eliminate antigen-low myeloma in an immunocompetent mouse model. Blood 144 (2) (2024)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-Related Colitis Is Associated with Fecal Microbial Dysbiosis and Can Be Mitigated by Fecal Microbiota Transplantation. Cancer immunology research 12 (3) (2024)
Ryan N Ptashkin, Mark D Ewalt, Gowtham Jayakumaran, Iwona Kiecka, Anita S Bowman, JinJuan Yao, Jacklyn Casanova, Yun-Te David Lin, Kseniya Petrova-Drus, Abhinita S Mohanty, Ruben Bacares, Jamal K Benhamida, Satshil Rana, Anna Razumova, Chad M Vanderbilt, Anoop Balakrishnan Rema, Ivelise Rijo, Julie Son-Garcia, Ino De Bruijn, Menglei Zhu, Sean Lachhander, Wei Wang, Mohammad S Haque, Venkatraman E Seshan, Jiajing Wang, Ying Liu, Khedoudja Nafa, Laetitia Borsu, Yanming Zhang, Umut Aypar, Sarah P Suehnholz, Debyani Chakravarty, Jae H Park, Omar Abdel-Wahab, Anthony R Mato, Wenbin Xiao, Mikhail Roshal, Mariko Yabe, Connie Lee Batlevi, Sergio Giralt, Gilles Andre Salles, Raajit K Rampal, Martin Tallman, Eytan M Stein, Anas Younes, Ross L Levine, Miguel-Ángel Perales, Marcel R M van den Brink, Ahmet Dogan, Marc Ladanyi, Michael F Berger, Angela Rose Brannon, Ryma Benayed, Ahmet Zehir, Maria E Arcila
Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing. Nature communications 14 (1) (2023)
Susan DeWolf, Yuval Elhanati, Katherine Nichols, Nicholas R Waters, Chi L Nguyen, John B Slingerland, Natasia Rodriguez, Olga Lyudovyk, Paul A Giardina, Anastasia I Kousa, Hana Andrlová, Nick Ceglia, Teng Fei, Rajya Kappagantula, Yanyun Li, Nathan Aleynick, Priscilla Baez, Rajmohan Murali, Akimasa Hayashi, Nicole Lee, Brianna Gipson, Madhumitha Rangesa, Zoe Katsamakis, Angel Dai, Amanda G Blouin, Maria E Arcila, Ignas Masilionis, Ronan Chaligné, Doris M Ponce, Heather J Landau, Ioannis Politikos, Roni Tamari, Alan M Hanash, Robert R Jenq, Sergio A Giralt, Kate A Markey, Yanming Zhang, Miguel-Ángel Perales, Nicholas D Socci, Benjamin D Greenbaum, Christine A Iacobuzio-Donahue, Travis J Hollman, Marcel R M van den Brink, Jonathan U Peled
Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse. Science translational medicine 15 (706) (2023)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation. Cancer immunology research (2023)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation. Cancer immunology research (2023)
Teng Fei, Tyler Funnell, Nicholas R Waters, Sandeep S Raj, Sean M Devlin, Angel Dai, Oriana Miltiadous, Roni Shouval, Meng Lv, Jonathan U Peled, Doris M Ponce, Miguel-Ángel Perales, Mithat Gönen, Marcel R M van den Brink
Scalable Log-ratio Lasso Regression Enhances Microbiome Feature Selection for Predictive Models. bioRxiv : the preprint server for biology (2023)
Teng Fei, Tyler Funnell, Nicholas R Waters, Sandeep S Raj, Sean M Devlin, Angel Dai, Oriana Miltiadous, Roni Shouval, Meng Lv, Jonathan U Peled, Doris M Ponce, Miguel-Ángel Perales, Mithat Gönen, Marcel R M van den Brink
Scalable Log-ratio Lasso Regression Enhances Microbiome Feature Selection for Predictive Models. bioRxiv : the preprint server for biology (2023)
Jonathan U Peled, Marcel R M van den Brink
Fecal Transplantation in Hematopoietic Transplantation. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Arielle Elkrief, Nicholas R Waters, Natalie Smith, Angel Dai, John B Slingerland, Nathan Aleynick, Binita Febles, Pooja Gogia, Nicholas D Socci, Melissa A Lumish, Paul A Giardina, Jamie E Chaft, Juliana Eng, Robert J Motzer, Robin B Mendelsohn, Kate A Markey, Mingqiang Zhuang, Yanyun Li, Zhifan Yang, Travis J Hollman, Charles M Rudin, Marcel R M van den Brink, Jinru Shia, Susan DeWolf, Adam J Schoenfeld, Matthew D Hellmann, N Esther Babady, David M Faleck, Jonathan U Peled
Immune-related colitis is associated with fecal microbial dysbiosis and can be mitigated by fecal microbiota transplantation. Cancer immunology research (2023)
Urvi A Shah, Kylee H Maclachlan, Andriy Derkach, Meghan Salcedo, Kelly Barnett, Julia Caple, Jenna Blaslov, Linh Tran, Amanda Ciardiello, Miranda Burge, Tala Shekarkhand, Peter A Adintori, Justin R Cross, Matthew J Pianko, Kinga K Hosszu, Devin McAvoy, Sham Mailankody, Neha Korde, Malin L Hultcrantz, Hani Hassoun, Carlyn Rose Tan, Sydney X Lu, Dhwani Patel, Benjamin T Diamond, Gunjan L Shah, Michael Scordo, Oscar B Lahoud, David J Chung, Heather J Landau, Saad Z Usmani, Sergio A Giralt, Ying Taur, Carl Ola Landgren, Gladys Block, Torin J Block, Jonathan U Peled, Marcel R M van den Brink, Alexander M Lesokhin
Sustained Minimal Residual Disease Negativity in Multiple Myeloma is Associated with Stool Butyrate and Healthier Plant-Based Diets. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (23) (2022)
Maria A Malik, Nathan W Sweeney, Mohammad Jafri, Andriy Derkach, Cynthia Chmielewski, Peter A Adintori, Sham Mailankody, Neha Korde, Carlyn R Tan, Hani Hassoun, Malin L Hultcrantz, Jens Hillengass, Susan E McCann, Neil Iyengar, Saad Usmani, Sergio A Giralt, Carl Ola Landgren, Marcel R M van den Brink, Jennifer M Ahlstrom, Alexander M Lesokhin, Anita D Souza, Susan Chimonas, Urvi A Shah
Nutrition perceptions, needs and practices among patients with plasma cell disorders. Blood cancer journal 12 (4) (2022)
Roni Shouval, Nicholas R Waters, Antonio L C Gomes, Corrado Zuanelli Brambilla, Teng Fei, Sean M Devlin, Chi L Nguyen, Kate A Markey, Angel Dai, John B Slingerland, Annelie G Clurman, Emily Fontana, Luigi A Amoretti, Roberta J Wright, Tobias M Hohl, Ying Taur, Anthony D Sung, Daniela Weber, Daigo Hashimoto, Takanori Teshima, Nelson J Chao, Ernst Holler, Michael Scordo, Sergio A Giralt, Miguel-Ángel Perales, Jonathan U Peled, Marcel R M van den Brink
Conditioning regimens are associated with distinct patterns of microbiota injury in allogeneic hematopoietic cell transplantation. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Jillian C Thompson, Yi Ren, Kristi Romero, Meagan Lew, Amy T Bush, Julia A Messina, Sin-Ho Jung, Sharareh Siamakpour-Reihani, Julie Miller, Robert R Jenq, Jonathan U Peled, Marcel R M van den Brink, Nelson J Chao, Mark G Shrime, Anthony D Sung
Financial incentives to increase stool collection rates for microbiome studies in adult bone marrow transplant patients. PloS one 17 (5) (2022)
Hana Andrlová, Oriana Miltiadous, Anastasia I Kousa, Angel Dai, Susan DeWolf, Sara Violante, Hee-Yon Park, Sudha Janaki-Raman, Rui Gardner, Sary El Daker, John Slingerland, Paul Giardina, Annelie Clurman, Antonio L C Gomes, Chi Nguyen, Marina Burgos da Silva, Gabriel K Armijo, Nicole Lee, Roberta Zappasodi, Ronan Chaligné, Ignas Masilionis, Emily Fontana, Doris M Ponce, Christina Cho, Amy T Bush, Lauren M Bohannon, Nelson J Chao, Anthony D Sung, Sergio A Giralt, Esther H Vidal, Kinga K Hosszu, Sean M Devlin, Jonathan U Peled, Justin R Cross, Miguel-Ángel Perales, Dale I Godfrey, Marcel R M van den Brink, Kate A Markey
MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT. Science translational medicine 14 (646) (2022)
Blossom Akagbosu, Zakieh Tayyebi, Gayathri Shibu, Yoselin A Paucar Iza, Deeksha Deep, Yollanda Franco Parisotto, Logan Fisher, H Amalia Pasolli, Valentin Thevin, Rasa Elmentaite, Maximilian Martin Ludwig Knott, Saskia Hemmers, Lorenz Jahn, Christin Friedrich, Jacob G Verter, Zhong-Min Wang, Marcel R M van den Brink, Georg Gasteiger, Thomas G P Grünewald, Julien C Marie, Christina S Leslie, Alexander Y Rudensky, Chrysothemis C Brown
Novel antigen-presenting cell imparts T reg -dependent tolerance to gut microbiota. Nature 610 (7933) (2022)
Jinyuan Yan, Chen Liao, Bradford P Taylor, Emily Fontana, Luigi A Amoretti, Roberta J Wright, Eric R Littmann, Anqi Dai, Nicholas R Waters, Jonathan U Peled, Ying Taur, Miguel-Ángel Perales, Benjamin A Siranosian, Ami S Bhatt, Marcel R M van den Brink, Eric G Pamer, Jonas Schluter, Joao B Xavier
A compilation of fecal microbiome shotgun metagenomics from hematopoietic cell transplantation patients. Scientific data 9 (1) (2022)
Zaker I Schwabkey, Diana H Wiesnoski, Chia-Chi Chang, Wen-Bin Tsai, Dung Pham, Saira S Ahmed, Tomo Hayase, Miriam R Ortega Turrubiates, Rawan K El-Himri, Christopher A Sanchez, Eiko Hayase, Annette C Frenk Oquendo, Takahiko Miyama, Taylor M Halsey, Brooke E Heckel, Alexandria N Brown, Yimei Jin, Mathilde Raybaud, Rishika Prasad, Ivonne Flores, Lauren McDaniel, Valerie Chapa, Philip L Lorenzi, Marc O Warmoes, Lin Tan, Alton G Swennes, Stephanie Fowler, Margaret E Conner, Kevin J McHugh, Tyler P Graf, Vanessa B Jensen, Christine B Peterson, Kim-Anh Do, Liangliang Zhang, Yushu Shi, Yinghong Wang, Jessica R Galloway-Peña, Pablo C Okhuysen, Carrie R Daniel-MacDougall, Yusuke Shono, Marina Burgos da Silva, Jonathan U Peled, Marcel R M van den Brink, Nadim J Ajami, Jennifer A Wargo, Pavan Reddy, Raphael H Valdivia, Lauren E Davey, Gabriela Rondon, Samer A Srour, Rohtesh S Mehta, Amin M Alousi, Elizabeth J Shpall, Richard E Champlin, Samuel A Shelburne Iii, Jeffrey J Molldrem, Mohamed A Jamal, Jennifer L Karmouch, Robert R Jenq
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Science translational medicine 14 (671) (2022)
Melody Smith, Anqi Dai, Guido Ghilardi, Kimberly V Amelsberg, Sean M Devlin, Raymone Pajarillo, John B Slingerland, Silvia Beghi, Pamela S Herrera, Paul Giardina, Annelie Clurman, Emmanuel Dwomoh, Gabriel Armijo, Antonio L C Gomes, Eric R Littmann, Jonas Schluter, Emily Fontana, Ying Taur, Jae H Park, Maria Lia Palomba, Elizabeth Halton, Josel Ruiz, Tania Jain, Martina Pennisi, Aishat Olaide Afuye, Miguel-Ángel Perales, Craig W Freyer, Alfred Garfall, Shannon Gier, Sunita Nasta, Daniel Landsburg, James Gerson, Jakub Svoboda, Justin Cross, Elise A Chong, Sergio Giralt, Saar I Gill, Isabelle Riviere, David L Porter, Stephen J Schuster, Michel Sadelain, Noelle Frey, Renier J Brentjens, Carl H June, Eric G Pamer, Jonathan U Peled, Andrea Facciabene, Marcel R M van den Brink, Marco Ruella
Author Correction: Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Nature medicine (2022)
Marina Burgos da Silva, Doris M Ponce, Angel Dai, Sean M Devlin, Antonio L C Gomes, Gillian Moore, John Slingerland, Roni Shouval, Gabriel K Armijo, Susan DeWolf, Teng Fei, Annelie Clurman, Emily Fontana, Luigi A Amoretti, Roberta J Wright, Hana Andrlová, Oriana Miltiadous, Miguel-Ángel Perales, Ying Taur, Jonathan U Peled, Marcel R M van den Brink
Preservation of the fecal microbiome is associated with reduced severity of graft-versus-host disease. Blood 140 (22) (2022)
Yongxian Hu, Jingjing Li, Fang Ni, Zhongli Yang, Xiaohua Gui, Zhiwei Bao, Houli Zhao, Guoqing Wei, Yiyun Wang, Mingming Zhang, Ruimin Hong, Linqin Wang, Wenjun Wu, Mohamad Mohty, Arnon Nagler, Alex H Chang, Marcel R M van den Brink, Ming D Li, He Huang
CAR-T cell therapy-related cytokine release syndrome and therapeutic response is modulated by the gut microbiome in hematologic malignancies. Nature communications 13 (1) (2022)
Melody Smith, Anqi Dai, Guido Ghilardi, Kimberly V Amelsberg, Sean M Devlin, Raymone Pajarillo, John B Slingerland, Silvia Beghi, Pamela S Herrera, Paul Giardina, Annelie Clurman, Emmanuel Dwomoh, Gabriel Armijo, Antonio L C Gomes, Eric R Littmann, Jonas Schluter, Emily Fontana, Ying Taur, Jae H Park, Maria Lia Palomba, Elizabeth Halton, Josel Ruiz, Tania Jain, Martina Pennisi, Aishat Olaide Afuye, Miguel-Ángel Perales, Craig W Freyer, Alfred Garfall, Shannon Gier, Sunita Nasta, Daniel Landsburg, James Gerson, Jakub Svoboda, Justin Cross, Elise A Chong, Sergio Giralt, Saar I Gill, Isabelle Riviere, David L Porter, Stephen J Schuster, Michel Sadelain, Noelle Frey, Renier J Brentjens, Carl H June, Eric G Pamer, Jonathan U Peled, Andrea Facciabene, Marcel R M van den Brink, Marco Ruella
Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy. Nature medicine 28 (4) (2022)
Thierry Rolling, Bing Zhai, Mergim Gjonbalaj, Nicholas Tosini, Keiko Yasuma-Mitobe, Emily Fontana, Luigi A Amoretti, Roberta J Wright, Doris M Ponce, Miguel-Ángel Perales, Joao B Xavier, Marcel R M van den Brink, Kate A Markey, Jonathan U Peled, Ying Taur, Tobias M Hohl
Haematopoietic cell transplantation outcomes are linked to intestinal mycobiota dynamics and an expansion of Candida parapsilosis complex species. Nature microbiology 6 (12) (2021)
Alexander H Schmidt, Deborah Buk, Stefanie N Bernas, Thilo Mengling, Elke Neujahr, Marcel R M van den Brink
A DKMS (German Bone Marrow Donor Center) view on cryopreservation of unrelated donor stem cell products during the Covid-19 pandemic. American journal of hematology 96 (3) (2021)
Qingxiao Song, Xiaoning Wang, Xiwei Wu, Tae Hyuk Kang, Hanjun Qin, Dongchang Zhao, Robert R Jenq, Marcel R M van den Brink, Arthur D Riggs, Paul J Martin, Yuan-Zhong Chen, Defu Zeng
IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice. Nature communications 12 (1) (2021)
Enrico Velardi, Jennifer J Tsai, Marcel R M van den Brink
T cell regeneration after immunological injury. Nature reviews. Immunology 21 (5) (2020)
Christoph K Stein-Thoeringer, Katherine Nichols, A Lazrak, Melissa Docampo, A E Slingerland, J B Slingerland, A G Clurman, G Armijo, Antonio L C Gomes, Yusuke Shono, Anna Staffas, Marina Burgos da Silva, S M Devlin, Kate A Markey, D Bajic, R Pinedo, A Tsakmaklis, Eric R Littmann, Alessandro Pastore, Ying Taur, Sebastien Monette, M E Arcila, A J Pickard, M Maloy, Roberta J Wright, Luigi A Amoretti, E Fontana, Dung Pham, M A Jamal, D Weber, A D Sung, Daigo Hashimoto, C Scheid, Joao B Xavier, Julia A Messina, K Romero, M Lew, Amy T Bush, Lauren M Bohannon, K Hayasaka, Yuta Hasegawa, M J G T Vehreschild, J R Cross, D M Ponce, Miguel-Ángel Perales, Sergio A Giralt, Robert R Jenq, Takanori Teshima, E Holler, Nelson J Chao, Eric G Pamer, Jonathan U Peled, Marcel R M van den Brink
Lactose drives Enterococcus expansion to promote graft-versus-host disease. Science (New York, N.Y.) 366 (6469) (2020)
Simon Heidegger, Alexander Wintges, Florian Stritzke, Sarah Bek, Katja Steiger, Paul-Albert Koenig, Sascha Göttert, Thomas Engleitner, Rupert Öllinger, Tatiana Nedelko, Julius Clemens Fischer, Vladimir Makarov, Christof Winter, Roland Rad, Marcel R M van den Brink, Juergen Ruland, Florian Bassermann, Timothy A Chan, Tobias Haas, Hendrik Poeck
RIG-I activation is critical for responsiveness to checkpoint blockade. Science immunology 4 (39) (2020)
Matthew J Pianko, Sean M Devlin, Eric R Littmann, Aisara Chansakul, Donna Mastey, Meghan Salcedo, Emily Fontana, Lilan Ling, Elizabet Tavitian, John B Slingerland, Ann E Slingerland, Annelie Clurman, Antonio L C Gomes, Ying Taur, Eric G Pamer, Jonathan U Peled, Marcel R M van den Brink, Carl Ola Landgren, Alexander M Lesokhin
Minimal residual disease negativity in multiple myeloma is associated with intestinal microbiota composition. Blood advances 3 (13) (2020)
Hao Guo, Wei-Chun Chou, Yunjia Lai, Kaixin Liang, Jason W Tam, Willie June Brickey, Liang Chen, Nathan D Montgomery, Xin Li, Lauren M Bohannon, Anthony D Sung, Nelson J Chao, Jonathan U Peled, Antonio L C Gomes, Marcel R M van den Brink, Matthew J French, Andrew N Macintyre, Gregory D Sempowski, Xianming M Tan, R Balfour Sartor, Kun Lu, Jenny P Y Ting
Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites. Science (New York, N.Y.) 370 (6516) (2020)
Jonas Schluter, Jonathan U Peled, Bradford P Taylor, Kate A Markey, Melody Smith, Ying Taur, Rene Niehus, Anna Staffas, Anqi Dai, Emily Fontana, Luigi A Amoretti, Roberta J Wright, Sejal Morjaria, Maly Fenelus, Melissa S Pessin, Nelson J Chao, Meagan Lew, Lauren Bohannon, Amy Bush, Anthony D Sung, Tobias M Hohl, Miguel-Ángel Perales, Marcel R M van den Brink, Joao B Xavier
The gut microbiota is associated with immune cell dynamics in humans. Nature 588 (7837) (2020)
Ying Taur, Katharine Z Coyte, Jonas Schluter, Elizabeth Robilotti, Cesar Figueroa, Mergim Gjonbalaj, Eric R Littmann, Lilan Ling, Liza Miller, Yangtsho Gyaltshen, Emily Fontana, Sejal Morjaria, Boglarka Gyurkocza, Miguel-Angel Perales, Hugo Castro-Malaspina, Roni Tamari, Doris Ponce, Guenther Koehne, Juliet N Barker, Ann Jakubowski, Esperanza Papadopoulos, Parastoo Dahi, Craig Sauter, Brian Shaffer, James W Young, Jonathan U Peled, Richard C Meagher, Robert R Jenq, Marcel R M van den Brink, Sergio A Giralt, Eric G Pamer, Joao B Xavier
Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant. Science translational medicine 10 (460) (2019)
Tobias Wertheimer, Enrico Velardi, Jennifer J Tsai, Kirsten Cooper, Shiyun Xiao, Christopher C Kloss, Katja J Ottmüller, Zeinab Mokhtari, Christian Brede, Paul deRoos, Sinéad Kinsella, Brisa Palikuqi, Michael Ginsberg, Lauren F Young, Fabiana Maria Kreines, Sophia R Lieberman, Amina Lazrak, Peipei Guo, Florent Malard, Odette M Smith, Yusuke Shono, Robert R Jenq, Alan M Hanash, Daniel J Nolan, Jason M Butler, Andreas Beilhack, Nancy R Manley, Shahin Rafii, Jarrod A Dudakov, Marcel R M van den Brink
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Science immunology 3 (19) (2018)
Matthew T Sorbara, Krista Dubin, Eric R Littmann, Thomas U Moody, Emily Fontana, Ruth Seok, Ingrid M Leiner, Ying Taur, Jonathan U Peled, Marcel R M van den Brink, Yael Litvak, Andreas J Bäumler, Jean-Luc Chaubard, Amanda J Pickard, Justin R Cross, Eric G Pamer
Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification. The Journal of experimental medicine 216 (1) (2018)
Jennifer J Tsai, Enrico Velardi, Yusuke Shono, Kimon V Argyropoulos, Amanda M Holland, Odette M Smith, Nury L Yim, Uttam K Rao, Fabiana M Kreines, Sophie R Lieberman, Lauren F Young, Amina Lazrak, Salma Youssef, Ya-Yuan Fu, Chen Liu, Cecilia Lezcano, George F Murphy, Il-Kang Na, Robert R Jenq, Alan M Hanash, Jarrod A Dudakov, Marcel R M van den Brink
Nrf2 regulates CD4+ T cell-induced acute graft-versus-host disease in mice. Blood 132 (26) (2018)
Jarrod A Dudakov, Anna M Mertelsmann, Margaret H O'Connor, Robert R Jenq, Enrico Velardi, Lauren F Young, Odette M Smith, Richard L Boyd, Marcel R M van den Brink, Alan M Hanash
Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease. Blood 130 (7) (2017)
Seishi Kyoizumi, Yoshiko Kubo, Junko Kajimura, Kengo Yoshida, Tomonori Hayashi, Kei Nakachi, Malcolm A Moore, Marcel R M van den Brink, Yoichiro Kusunoki
Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. Journal of immunology (Baltimore, Md. : 1950) 199 (8) (2017)
Julius Clemens Fischer, Michael Bscheider, Gabriel Eisenkolb, Chia-Ching Lin, Alexander Wintges, Vera Otten, Caroline A Lindemans, Simon Heidegger, Martina Rudelius, Sebastien Monette, Kori A Porosnicu Rodriguez, Marco Calafiore, Sophie Liebermann, Chen Liu, Siegfried Weiss, Siegfried Weiss, Ulrich Kalinke, Jürgen Ruland, Christian Peschel, Yusuke Shono, Melissa Docampo, Enrico Velardi, Robert R Jenq, Alan M Hanash, Jarrod A Dudakov, Tobias Haas, Marcel R M van den Brink, Hendrik Poeck
RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury. Science translational medicine 9 (386) (2017)
Yu Matsuzawa-Ishimoto, Yusuke Shono, Luis E Gomez, Vanessa M Hubbard-Lucey, Michael Cammer, Jessica Neil, M Zahidunnabi Dewan, Sophia R Lieberman, Amina Lazrak, Jill M Marinis, Allison Beal, Philip A Harris, John Bertin, Chen Liu, Yi Ding, Marcel R M van den Brink, Ken H Cadwell
Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium. The Journal of experimental medicine 214 (12) (2017)
Shiyun Xiao, Ivo D Shterev, Wen Zhang, Lauren Young, Jae-Hung Shieh, Malcolm Moore, Marcel R M van den Brink, Gregory D Sempowski, Nancy R Manley
Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors. Journal of immunology (Baltimore, Md. : 1950) 199 (8) (2017)
Mohammed S Chaudhry, Enrico Velardi, Florent Malard, Marcel R M van den Brink
Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus. Journal of immunology (Baltimore, Md. : 1950) 198 (1) (2017)
Yusuke Shono, Marcel R M van den Brink
Empiric antibiotic use in allogeneic hematopoietic cell transplantation: should we avoid anaerobe coverage? Blood advances 1 (25) (2017)
Juhan Yoon, Juan Manuel Leyva Castillo, Guoxing Wang, Claire Galand, Michiko K Oyoshi, Lalit Kumar, Sabine Hoff, Rui He, Alexander Chervonsky, Joost J Oppenheim, Vijay K Kuchroo, Marcel R M van den Brink, Rene de Waal Malefyt, Philippe A Tessier, Robert C Fuhlbrigge, Philip Rosenstiel, Cox Terhorst, George Murphy, Raif S Geha
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. The Journal of experimental medicine 213 (10) (2016)
Anna Staffas, Marina Burgos da Silva, Marcel R M van den Brink
The intestinal microbiota in allogeneic hematopoietic cell transplant and graft-versus-host disease. Blood 129 (8) (2016)

Marcel R M van den Brink.css-eqlu8i{font-size:small;padding-left:4px;} (Marcel van den Brink, M R M van den Brink)

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Marcel R M van den Brink (Marcel van den Brink, M R M van den Brink)