Daily irradiation versus irradiation at two- to three-day intervals in stereotactic radiotherapy for patients with 1-5 brain metastases: study protocol for a multicenter open-label randomized phase II trial.

Natsuo TomitaHiromichi IshiyamaChiyoko MakitaYukihiko OhshimaAiko NagaiFumiya BabaMayu KunoShinya OtsukaTakuhito KondoChikao SugieTatsuya KawaiTaiki TakaokaDai OkazakiAkira ToriiMasanari NiwaNozomi KitaSeiya TakanoShogo KawakamiMasayuki MatsuoTomoyasu KumanoMakoto ItoSou AdachiSouichiro AbeTakayuki MuraoAkio Hiwatashi

Published in: BMC cancer (2022)

UMIN000048728. Date of registration: August 23, 2022. https://center6.umin.ac.jp/cgi-bin/ctr/ctr_view_reg.cgi?recptno=R000055515 .

Keyphrases

brain metastases
open label
small cell lung cancer
phase iii
phase ii
radiation induced
clinical trial
phase ii study
double blind
study protocol
early stage
placebo controlled
radiation therapy
physical activity
locally advanced
randomized controlled trial
cross sectional