Electronic Versus Traditional Data Collection: A Multicenter Randomized Controlled Perioperative Pain Trial.
James S KhanLindsay A JibbJason Walter BusseIan GilronStephen ChoiJames E PaulMichael McGillionSean MackeyD Norman BuckleyShun Fu LeeP J DevereauxPublished in: Canadian journal of pain = Revue canadienne de la douleur (2019)
Background : Electronic data collection is increasingly available as a means to collect pain-related clinical trial data; however, effectiveness and costs relative to traditional data collection are uncertain. Aims : The aim of this study was to evaluate data quality, protocol adherence, satisfaction, and resource requirements of electronic data collection (i.e., Internet-based electronic submission) compared to traditional data collection methods (i.e., paper-based diaries and telephone interviews) in a perioperative factorial randomized controlled trial. Methods : This study was an open-label two-arm parallel randomized controlled trial. Women (18-75 years) undergoing breast cancer surgery were allocated to either electronic or traditional data collection and completed pain-related questionnaires at baseline, postoperative period, and 3-month follow-up (NCT02240199). Results : We acquired outcome data at all time points from 78 randomized patients, 38 in the electronic group and 40 in the traditional group. The number of data queries (e.g., erroneously entered data) per patient was higher in the electronic data group (4.92 [SD = 4.67] vs. 1.88 [SD = 1.51]; P < 0.001). No between-group differences were observed for compliance with medications, data completeness, loss to follow-up, or patient or research assistant satisfaction. More research assistant time per patient was spent collecting data in the traditional group (42.6 min [SD = 12.8] vs. 9.92 min [SD = 7.6]; P < 0.001); however, costs per patient were higher in the electronic group ($176.85 [SD = 2.90] vs. $16.33 [SD = 4.90]; P < 0.001). Conclusion : Electronic data collection is feasible for perioperative pain clinical trials. Additional trials, including different surgical populations, are needed to confirm our findings and optimize use of electronic data capture methods.
Keyphrases
- electronic health record
- clinical trial
- randomized controlled trial
- big data
- study protocol
- healthcare
- type diabetes
- cardiac surgery
- systematic review
- adipose tissue
- acute kidney injury
- machine learning
- pregnant women
- metabolic syndrome
- phase iii
- open label
- neuropathic pain
- cross sectional
- end stage renal disease
- acute coronary syndrome
- ejection fraction
- atrial fibrillation
- peritoneal dialysis
- glycemic control