Efficacy and Safety of Sinomenine Preparation for Ankylosing Spondylitis: A Systematic Review and Meta-Analysis of Clinical Randomized Controlled Trials.

Shan-Shan Lin Chun-Xiang Liu Jun-Hua Zhang Hui WangJing-Bo ZhaiJing-Yuan Mao Xian-Liang Wang

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

This study shows that oral SP may be effective and safe in the treatment of AS. Due to the low methodological quality of the included RCTs and the limitations of the meta-analysis, it is still necessary to carry out more multicenter, large-sample, and high-quality RCTs to further verify the conclusions. The review protocol was registered on PROSPERO (CRD42018099170), and the review was constructed following the PRISMA guidelines (Annex 1).

Keyphrases

ankylosing spondylitis
meta analyses
randomized controlled trial
systematic review
rheumatoid arthritis
disease activity
wastewater treatment
clinical trial
cross sectional
clinical practice
systemic lupus erythematosus
study protocol
high resolution
combination therapy
replacement therapy