Accelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a novel oral vaccine using a human challenge model of Salmonella Paratyphi A infection in healthy adult volunteers.

Naina McCannKatherine EmaryNisha SinghFlorence McleanSusana CamaraElizabeth JonesYoung Chan KimXinxue LiuMelanie GreenlandKerry ConlinJennifer HillMarije VerheulHannah RobinsonBrian AngusMaheshi N RamasamyMyron M LevineAndrew J Pollard

Published in: BMJ open (2023)

ISRCTN15485902.

Keyphrases

escherichia coli
listeria monocytogenes
endothelial cells
clinical trial
open label
study protocol
induced pluripotent stem cells
double blind
pluripotent stem cells
placebo controlled
randomized controlled trial