Curcumin and zinc co-supplementation along with a loss-weight diet can improve lipid profiles in subjects with prediabetes: a multi-arm, parallel-group, randomized, double-blind placebo-controlled phase 2 clinical trial.
Majid KarandishHassan Mozaffari-KhosraviSeyed Mohammad MohammadiBahman CheraghianMaryam AzhdariPublished in: Diabetology & metabolic syndrome (2022)
The beneficial effects of "curcumin and zinc" co-supplementation was reported for the changes of some lipid profiles (TG, LDL, HDL, non-HDL, and HDL to LDL ratio), BMI, and weight with no positive effects on TC, dietary intake, PA, WC, and HC. Therefore, it may play a potential role in the prevention of macro and microvascular complications. Trial registration The project is a registered clinical trial (Registration number: IRCT20190902044671N1, Iranian Registry of Clinical Trials (IRCT), registered October 11, 2019.
Keyphrases
- clinical trial
- double blind
- placebo controlled
- phase iii
- phase ii
- body mass index
- weight loss
- physical activity
- study protocol
- weight gain
- open label
- oxide nanoparticles
- fatty acid
- phase ii study
- low density lipoprotein
- randomized controlled trial
- quality improvement
- squamous cell carcinoma
- risk factors
- body weight
- radiation therapy