Gene Expression-Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial.
Karolina EdlundKatrin MadjarAntje LebrechtBahriye AktaşHenryk PilchGerald HoffmannManfred HofmannHans-Christian KolbergDaniel BoehmMarco BattistaMartina SeehaseKathrin StewenSusanne GebhardCristina CadenasRosemarie MarchanWalburgis BrennerAnnette HasenburgHeinz KoelblChristine SolbachMathias GehrmannBerno TannerKarsten E WeberSibylle LoiblAgapios SachinidisJörg RahnenführerMarcus SchmidtJan G HengstlerPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
The novel 20-gene classifier reliably identifies patients who do not achieve a pCR in about one third of luminal breast cancers in both the EXPRESSION and combined validation cohorts.