MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes.

David MoulinVéronique SaloneMeriem KoufanyThomas ClémentIsabelle Behm-AnsmantChristiane BranlantBruno CharpentierJean-Yves Jouzeau

Published in: BioMed research international (2017)

By acting probably as a posttranscriptional regulator with a different efficacy on COL2A1 and COL1A2 expression, miR-29b can contribute to the collagens imbalance associated with an abnormal chondrocyte phenotype.

Keyphrases

endothelial cells
poor prognosis
induced pluripotent stem cells
transcription factor
pluripotent stem cells
binding protein