Our results indicate that the alteration of Ftx expression induces proteomic changes in highly metastatic HCT116 cells, suggesting that Ftx and its downstream molecules and signaling pathways could be potential diagnostic biomarkers and therapeutic targets for metastatic CRC.
Keyphrases
- long noncoding rna
- cell cycle arrest
- pi k akt
- induced apoptosis
- cell death
- signaling pathway
- squamous cell carcinoma
- small cell lung cancer
- endothelial cells
- poor prognosis
- binding protein
- induced pluripotent stem cells
- cell proliferation
- oxidative stress
- protein protein
- pluripotent stem cells
- amino acid
- epithelial mesenchymal transition
- small molecule
- label free