Exercise intervention on cardiorespiratory fitness in rheumatoid arthritis patients with high cardiovascular disease risk: a single-arm pilot study.
M SobejanaJ van den HoekGeorgios S MetsiosGeorge D KitasMarike van der LeedenS VerberneHarald T JørstadMirjam PijnappelsWillem F LemsMichael T NurmohamedM van der EschPublished in: Clinical rheumatology (2022)
A 12-week exercise intervention seems to be safe and improves cardiorespiratory fitness and disease activity in patients with RA with a high risk for cardiovascular diseases. Key Points 1. Rheumatoid arthritis patients with high cardiovascular disease risk were able to perform a maximum exercise test and a 12-week aerobic-based medium-to-high intensity exercise intervention. 2. The exercise intervention improved cardiorespiratory fitness and disease activity in rheumatoid arthritis patients with high cardiovascular disease risk. 3. Cardiorespiratory fitness levels were still low post-exercise intervention (i.e. 18.15 ml.kg-1min-1 compared to the 20.9 ml.kg-1min-1 baseline mean of the RA patients without CVD risk).
Keyphrases
- disease activity
- high intensity
- rheumatoid arthritis
- rheumatoid arthritis patients
- cardiovascular disease
- systemic lupus erythematosus
- ankylosing spondylitis
- resistance training
- randomized controlled trial
- juvenile idiopathic arthritis
- physical activity
- interstitial lung disease
- type diabetes
- clinical trial
- ejection fraction
- end stage renal disease
- newly diagnosed
- cardiovascular events
- coronary artery disease
- peritoneal dialysis
- patient reported outcomes