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Isolation and Characterization of Human Colon Adenocarcinoma Stem-Like Cells Based on the Endogenous Expression of the Stem Markers.

Sergei A KoshkinOlga V AnatskayaAlexander E VinogradovVladimir N UverskyGuy W DayhoffMargarita A BystriakovaValery A PospelovElena N Tolkunova
Published in: International journal of molecular sciences (2021)
The use of the SORE6x reporter construct for CSCs enrichment allows us to obtain CSC-like population that can be used as a model to search for the new prognostic factors and potential therapeutic targets for colon cancer treatment.
Keyphrases
  • prognostic factors
  • endothelial cells
  • poor prognosis
  • squamous cell carcinoma
  • induced pluripotent stem cells
  • crispr cas
  • pluripotent stem cells
  • locally advanced
  • risk assessment
  • radiation therapy