Comparable Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Basal Fuel Metabolism and Insulin Sensitivity in Individuals with Obesity and Type 2 Diabetes.
Katrine BrodersenMichael F NielsenBjørn RichelsenEsben S LauritzenEinar PahleJan AbrahamsenBolette HartmannJens J HolstNiels MøllerPublished in: Journal of diabetes research (2022)
Our data suggest that RYGB and SG improve basal fuel metabolism and two-step insulin sensitivity in the liver, muscle, and fat and seem equally favourable when investigated 2 months after surgery. This trial is registered with NCT02713555.
Keyphrases
- roux en y gastric bypass
- weight loss
- type diabetes
- gastric bypass
- bariatric surgery
- obese patients
- insulin resistance
- glycemic control
- adipose tissue
- skeletal muscle
- metabolic syndrome
- electronic health record
- clinical trial
- study protocol
- phase iii
- phase ii
- cardiovascular disease
- big data
- high fat diet induced
- fatty acid
- randomized controlled trial
- open label
- high resolution
- machine learning
- mass spectrometry
- atomic force microscopy
- body mass index
- high speed