Pattern of disease progression during third-line or later chemotherapy with nivolumab associated with poor prognosis in advanced gastric cancer: a multicenter retrospective study in Japan.
Masahiko AokiShigenori KadowakiNaoki TakahashiTakeshi SuzukiKotoe OshimaTakayuki AndoYoshiyuki YamamotoKentaro KawakamiYosuke KitoToshihiko MatsumotoKeitaro ShimozakiYasuhiro MiyazakiToshifumi YamaguchiMichitaka NagaseTakao TamuraYusuke AmanumaTaito EsakiYuji MiuraKohei AkiyoshiEishi BabaAkitaka MakiyamaYuji NegoroKoji NakashimaNaotoshi SugimotoKengo NagashimaHirokazu ShojiNarikazu BokuPublished in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2022)
New lesions in different organs and appearance/increase of ascites, rather than the original definition of HPD, are the patterns of disease progression associated with poor prognosis in AGC patients receiving nivolumab whose best response was PD.