SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol.

Aude EspinasseOlga SolovyevaMunyaradzi DimairoChristopher J WeirThomas JakiAdrian ManderAndrew KightleyJeffry EvansShing LeeAlun BeddingSally HopewellKhadija RantellRong LiuAn-Wen ChanJohann De BonoChristina Yap

Published in: BMJ open (2023)

SPIRIT-DEFINE and CONSORT-DEFINE are registered with the EQUATOR Network.

Keyphrases

clinical trial
study protocol
randomized controlled trial
double blind
phase ii