Christina Yap

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 35

Top Venues

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

JCO precision oncology

Archives of disease in childhood. Education and practice edition

The Institute of Cancer Research

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Institute of Cancer Research Jun 01 2019

United Kingdom

Professor of Clinical Trials Biostatistics :: Clinical Trials and Statistics Unit

Publications

Robin Chatters, Munyaradzi Dimairo, Cindy Cooper, Shamila Ditta, Jonathan Woodward, Katie Biggs, Della Ogunleye, Fiona Thistlethwaite, Christina Yap, Alexander Rothman
Exploring the barriers to, and importance of, participant diversity in early-phase clinical trials: an interview-based qualitative study of professionals and patient and public representatives. BMJ open 14 (3) (2024)
Robin Chatters, Munyaradzi Dimairo, Cindy Cooper, Shamila Ditta, Jonathan Woodward, Katie Biggs, Della Ogunleye, Fiona Thistlethwaite, Christina Yap, Alexander Rothman
Exploring the barriers to, and importance of, participant diversity in early-phase clinical trials: an interview-based qualitative study of professionals and patient and public representatives. BMJ open 14 (3) (2024)
Zhulin Yin, Adrian P Mander, Johann S de Bono, Haiyan Zheng, Christina Yap
Handling Incomplete or Late-Onset Toxicities in Early-Phase Dose-Finding Clinical Trials: Current Practice and Future Prospects. JCO precision oncology 8 (2024)
Zhulin Yin, Adrian P Mander, Johann S de Bono, Haiyan Zheng, Christina Yap
Handling Incomplete or Late-Onset Toxicities in Early-Phase Dose-Finding Clinical Trials: Current Practice and Future Prospects. JCO precision oncology 8 (2024)
Robin Chatters, Munyaradzi Dimairo, Cindy Cooper, Shamila Ditta, Jonathan Woodward, Katie Biggs, Della Ogunleye, Fiona Thistlethwaite, Christina Yap, Alexander Rothman
Exploring the barriers to, and importance of, participant diversity in early-phase clinical trials: an interview-based qualitative study of professionals and patient and public representatives. BMJ open 14 (3) (2024)
Zhulin Yin, Adrian P Mander, Johann S de Bono, Haiyan Zheng, Christina Yap
Handling Incomplete or Late-Onset Toxicities in Early-Phase Dose-Finding Clinical Trials: Current Practice and Future Prospects. JCO precision oncology 8 (2024)
Aude Espinasse, Olga Solovyeva, Munyaradzi Dimairo, Christopher J Weir, Thomas Jaki, Adrian Mander, Andrew Kightley, Jeffry Evans, Shing Lee, Alun Bedding, Sally Hopewell, Khadija Rantell, Rong Liu, An-Wen Chan, Johann De Bono, Christina Yap
SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol. BMJ open 13 (3) (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
Aude Espinasse, Olga Solovyeva, Munyaradzi Dimairo, Christopher J Weir, Thomas Jaki, Adrian Mander, Andrew Kightley, Jeffry Evans, Shing Lee, Alun Bedding, Sally Hopewell, Khadija Rantell, Rong Liu, An-Wen Chan, Johann De Bono, Christina Yap
SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol. BMJ open 13 (3) (2023)
Claire N Harrison, Jyoti Nangalia, Rebecca Boucher, Aimee Jackson, Christina Yap, Jennifer O'Sullivan, Sonia Fox, Isaak Ailts, Amylou C Dueck, Holly L Geyer, Ruben A Mesa, William G Dunn, Eugene Nadezhdin, Natalia Curto-Garcia, Anna Green, Bridget Wilkins, Jason Coppell, John Laurie, Mamta Garg, Joanne Ewing, Stephen Knapper, Josephine Crowe, Frederick Chen, Ioannis Koutsavlis, Anna Godfrey, Siamak Arami, Mark Drummond, Jennifer L Byrne, Fiona Clark, Carolyn Mead-Harvey, Elizabeth Joanna Baxter, Mary Frances Frances McMullin, Adam J Mead
Ruxolitinib Versus Best Available Therapy for Polycythemia Vera Intolerant or Resistant to Hydroxycarbamide in a Randomized Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Aude Espinasse, Olga Solovyeva, Munyaradzi Dimairo, Christopher J Weir, Thomas Jaki, Adrian Mander, Andrew Kightley, Jeffry Evans, Shing Lee, Alun Bedding, Sally Hopewell, Khadija Rantell, Rong Liu, An-Wen Chan, Johann De Bono, Christina Yap
SPIRIT and CONSORT extensions for early phase dose-finding clinical trials: the DEFINE (DosE-FIndiNg Extensions) study protocol. BMJ open 13 (3) (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
Christina Yap, Olga Solovyeva, Johann S de Bono, Jan Rekowski, Dhrusti Patel, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Richard Wilson Peck, Kathryn S Hayward, Sally Hopewell, Moreno Ursino, Khadija Rerhou Rantell, Melanie Jane Calvert, Shing Lee, Andrew Kightley, Deborah Ashby, An-Wen Chan, Elizabeth Garrett-Mayer, John Dudley Isaacs, Robert Golub, Olga Kholmanskikh, Dawn P Richards, Oliver Boix, James Matcham, Lesley Seymour, Susan Percy Ivy, Lynley V Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan D Berlin, Aude Espinasse, Munyaradzi Dimairo, Christopher J Weir
Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ (Clinical research ed.) 383 (2023)
Christina Yap, Jan Rekowski, Moreno Ursino, Olga Solovyeva, Dhrusti Patel, Munyaradzi Dimairo, Christopher J Weir, An-Wen Chan, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Richard Wilson Peck, Kathryn S Hayward, Melanie Jane Calvert, Khadija Rerhou Rantell, Shing Lee, Andrew Kightley, Sally Hopewell, Deborah Ashby, Elizabeth Garrett-Mayer, John Dudley Isaacs, Robert Golub, Olga Kholmanskikh, Dawn P Richards, Oliver Boix, James Matcham, Lesley Seymour, Susan Percy Ivy, Lynley V Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan D Berlin, Aude Espinasse, Johann S de Bono
Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ (Clinical research ed.) 383 (2023)
Olga Solovyeva, Munyaradzi Dimairo, Christopher J Weir, Siew Wan Hee, Aude Espinasse, Moreno Ursino, Dhrusti Patel, Andrew Kightley, Sarah Hughes, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Shing Lee, Sally Hopewell, Khadija Rerhou Rantell, An-Wen Chan, Alun Bedding, Richard Stephens, Dawn P Richards, Lesley Roberts, John Kirkpatrick, Johann S de Bono, Christina Yap
Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study. BMC medicine 21 (1) (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
Christina Guo, Adam Sharp, Bora Gurel, Mateus Crespo, Ines Figueiredo, Suneil Jain, Ursula Vogl, Jan Rekowski, Mahtab Rouhifard, Lewis Gallagher, Wei Yuan, Suzanne Carreira, Khobe Chandran, Alec Paschalis, Ilaria Colombo, Anastasios Stathis, Claudia Bertan, George Seed, Jane Goodall, Florence I Raynaud, Ruth Ruddle, Karen E Swales, Jason Malia, Denisa Bogdan, Crescens Tiu, Reece Caldwell, Caterina Aversa, Ana Ferreira, Antje Neeb, Nina Tunariu, Daniel Westaby, Juliet Carmichael, Maria de Los Dolores Fenor de la Maza, Christina Yap, Ruth Matthews, Hannah Badham, Toby Prout, Alison Turner, Mona Parmar, Holly Tovey, Ruth Riisnaes, Penny Flohr, Jesús Gil, David Waugh, Shaun Decordova, Anna Schlag, Bianca Calì, Andrea Alimonti, Johann S de Bono
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance. Nature (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, George Clarke, Yuri L Boteon, Darren Barton, Desley A H Neil, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, Bobby V M Dasari, James W Ferguson, Hentie Cilliers, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, M Thamara P R Perera, Darius F Mirza
Discarded livers tested by normothermic machine perfusion in the VITTAL trial: Secondary end points and 5-year outcomes. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 30 (1) (2023)
James M S Wason, Munyaradzi Dimairo, Katie Biggs, Sarah Bowden, Julia M Brown, Laura Flight, Jamie Hall, Thomas F Jaki, Rachel Lowe, Philip Pallmann, Mark A Pilling, Claire Snowdon, Matthew Robert Sydes, Sofía S Villar, Christopher J Weir, Nina Wilson, Christina Yap, Helen C Hancock, Rebecca H Maier
Practical guidance for planning resources required to support publicly-funded adaptive clinical trials. BMC medicine 20 (1) (2022)
Ethan M Basch, Christina Yap
Patient-Reported Outcomes for Tolerability Assessment in Phase I Cancer Clinical Trials. Journal of the National Cancer Institute 113 (8) (2022)
Christina Yap, Alun Bedding, Johann de Bono, Munyaradzi Dimairo, Aude Espinasse, Jeffry Evans, Sally Hopewell, Thomas Jaki, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Olga Solovyeva, Christopher J Weir
The need for reporting guidelines for early phase dose-finding trials: Dose-Finding CONSORT Extension. Nature medicine 28 (1) (2022)
Dionysis Papadatos-Pastos, Wei Yuan, Abhijit Pal, Mateus Crespo, Ana Ferreira, Bora Gurel, Toby Prout, Malaka Ameratunga, Maxime Chénard-Poirier, Andra Curcean, Claudia Bertan, Chloe Baker, Susana Miranda, Nahal Masrour, Wentin Chen, Rita Pereira, Ines Figueiredo, Ricardo Morilla, Ben Jenkins, Anna Zachariou, Ruth Riisnaes, Mona Parmar, Alison Turner, Suzanne Carreira, Christina Yap, Robert Brown, Nina Tunariu, Udai Banerji, Juanita Lopez, Johann de Bono, Anna R Minchom
Phase 1, dose-escalation study of guadecitabine (SGI-110) in combination with pembrolizumab in patients with solid tumors. Journal for immunotherapy of cancer 10 (6) (2022)
Julia Lai-Kwon, Alyssa M Vanderbeek, Anna Minchom, Olalekan Lee Aiyegbusi, Della Ogunleye, Richard Stephens, Melanie Calvert, Christina Yap
Using Patient-Reported Outcomes in Dose-Finding Oncology Trials: Surveys of Key Stakeholders and the National Cancer Research Institute Consumer Forum. The oncologist 27 (9) (2022)
Julia Lai-Kwon, Zhulin Yin, Anna Minchom, Christina Yap
Trends in patient-reported outcome use in early phase dose-finding oncology trials - an analysis of ClinicalTrials.gov. Cancer medicine 10 (22) (2021)
Rebecca B Silva, Christina Yap, Richard Carvajal, Shing M Lee
Would the Recommended Dose Have Been Different Using Novel Dose-Finding Designs? Comparing Dose-Finding Designs in Published Trials. JCO precision oncology 5 (2021)
Abhijit Pal, Sarah E Stapleton, Christina Yap, Julia Lai-Kwon, Robert Daly, Dimitrios Magkos, Bindumalini Rao Baikady, Anna Minchom, Udai Banerji, Johann De Bono, Deme Karikios, Frances Boyle, Juanita Lopez
Study protocol for a randomised controlled trial of enhanced informed consent compared to standard informed consent to improve patient understanding of early phase oncology clinical trials (CONSENT). BMJ open 11 (9) (2021)
Hynek Mergental, Richard W Laing, Amanda J Kirkham, M Thamara P R Perera, Yuri Longatto Boteon, Joseph Attard, Darren Barton, Stuart Curbishley, Manpreet Wilkhu, Desley A H Neil, Stefan G Hübscher, Paolo Muiesan, John R Isaac, Keith J Roberts, Manuel Abradelo, Andrea Schlegel, James Ferguson, Hentie Cilliers, Julian Bion, David H Adams, Chris Morris, Peter J Friend, Christina Yap, Simon C Afford, Darius F Mirza
Transplantation of discarded livers following viability testing with normothermic machine perfusion. Nature communications 11 (1) (2020)
Anthony Kong, James Good, Amanda Kirkham, Joshua S Savage, Rhys Mant, Laura Llewellyn, Joanna Parish, Rachel Spruce, Martin Forster, Stefano Schipani, Kevin Harrington, Joseph Sacco, Patrick Murray, Gary Middleton, Christina Yap, Hisham Mehanna
Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: the WISTERIA trial protocol. BMJ open 10 (3) (2020)
Gerard Cathal Millen, Christina Yap
Adaptive trial designs: what are multiarm, multistage trials? Archives of disease in childhood. Education and practice edition 105 (6) (2019)
Philip Pallmann, Fang Wan, Adrian P Mander, Graham M Wheeler, Christina Yap, Sally Clive, Lisa V Hampson, Thomas F Jaki
Designing and evaluating dose-escalation studies made easy: The MoDEsT web app. Clinical trials (London, England) 17 (2) (2019)
Gerard Cathal Millen, Christina Yap
Adaptive trial designs: what is the continual reassessment method? Archives of disease in childhood. Education and practice edition 106 (3) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christina Yap