Four-Year Follow-up of [18 F]Fluorodeoxyglucose Positron Emission Tomography-Based Parkinson's Disease-Related Pattern Expression in 20 Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder Shows Prodromal Progression.
Rosalie V KoganAnnette JanzenSanne K MelesElisabeth SittigRemco J RenkenVita GurvitsGeert MayerKlaus L LeendersWolfgang H Oertelnull nullPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
Suprathreshold PD-related brain pattern expression and greater score rate of change may signify greater shorter-term risk for phenoconversion. Our results support the use of serial PD-related brain pattern expression measurements as a prodromal PD progression biomarker in patients with isolated rapid eye movement sleep behavior disorder. © 2020 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
- positron emission tomography
- poor prognosis
- computed tomography
- pet ct
- resting state
- binding protein
- white matter
- parkinson disease
- physical activity
- randomized controlled trial
- sleep quality
- long non coding rna
- preterm infants
- functional connectivity
- systematic review
- loop mediated isothermal amplification
- depressive symptoms
- drug induced
- meta analyses