PET imaging of HER2 expression with an 18F-fluoride labeled aptamer.

Hyun Jeong KimJun Young ParkYong Jin LeeIn Ho SongYe Lim ChoJu Ri ChaeHyungu KangJong Hoon LimJung Hwan LeeWon Jun Kang

Published in: PloS one (2019)

The 18F-labeled aptamer enabled appropriate visualization of HER2 expression by human breast cancer cells. The results suggest that a radiolabeled HER2 aptamer could potentially be applied in the development of treatment strategies or in targeted therapy against HER2-positive breast cancer cells.

Keyphrases

pet imaging
breast cancer cells
poor prognosis
gold nanoparticles
sensitive detection
magnetic nanoparticles
endothelial cells
positron emission tomography
label free
binding protein
computed tomography
long non coding rna
pluripotent stem cells
quantum dots