Effectiveness and Safety of Antithrombotic Medication in Patients With Atrial Fibrillation and Intracranial Hemorrhage: Systematic Review and Meta-Analysis.
Elena IvanyLeona A VermaGregory Yoke Hong LipRobyn R LottoDavid John WerringDeirdre A LanePublished in: Stroke (2022)
In nontraumatic ICrH survivors with atrial fibrillation, OAC therapy is associated with a reduced risk of thromboembolic events and all-cause mortality without significantly increasing risk of recurrent ICrH. This finding is primarily based on observational data, and further larger randomized controlled trials are needed to corroborate or refute these findings.
Keyphrases
- atrial fibrillation
- randomized controlled trial
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- direct oral anticoagulants
- electronic health record
- heart failure
- young adults
- healthcare
- percutaneous coronary intervention
- big data
- adverse drug
- cross sectional
- optic nerve
- systematic review
- stem cells
- coronary artery disease
- venous thromboembolism
- data analysis
- mesenchymal stem cells
- study protocol
- optical coherence tomography